[Term] id: PR:O35245-2 name: polycystin-2 isoform m2 (mouse) def: "A polycystin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35245-2." [PRO:DNx, UniProtKB:O35245] comment: Category=organism-sequence. synonym: "mPKD2/iso:m2" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta6 (mouse)" EXACT [UniProtKB:O35245] xref: UniProtKB:O35245-2 is_a: PR:O35245 ! polycystin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:O35245-3 name: polycystin-2 isoform m3 (mouse) def: "A polycystin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35245-3." [PRO:DNx, UniProtKB:O35245] comment: Category=organism-sequence. synonym: "mPKD2/iso:m3" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta7 (mouse)" EXACT [UniProtKB:O35245] xref: UniProtKB:O35245-3 is_a: PR:O35245 ! polycystin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:O35245-1 name: polycystin-2 isoform m1 (mouse) def: "A polycystin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35245-1." [PRO:DNx, UniProtKB:O35245] comment: Category=organism-sequence. synonym: "mPKD2/iso:m1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O35245-1 is_a: PR:O35245 ! polycystin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:O35245-4 name: polycystin-2 isoform m4 (mouse) def: "A polycystin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35245-4." [PRO:DNx, UniProtKB:O35245] comment: Category=organism-sequence. synonym: "mPKD2/iso:m4" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta9 (mouse)" EXACT [UniProtKB:O35245] xref: UniProtKB:O35245-4 is_a: PR:O35245 ! polycystin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:O35245-5 name: polycystin-2 isoform m5 (mouse) def: "A polycystin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35245-5." [PRO:DNx, UniProtKB:O35245] comment: Category=organism-sequence. synonym: "mPKD2/iso:m5" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta12/13 (mouse)" EXACT [UniProtKB:O35245] xref: UniProtKB:O35245-5 is_a: PR:O35245 ! polycystin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q13563 name: polycystin-2 (human) def: "A polycystin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13563] comment: Category=organism-gene. synonym: "PKD2" RELATED Gene-based [UniProtKB:Q13563] synonym: "TRPP2" RELATED Gene-based [UniProtKB:Q13563] synonym: "hPKD2" EXACT PRO-short-label [PRO:DNx] synonym: "PC2 (human)" BROAD [UniProtKB:Q13563] synonym: "R48321 (human)" EXACT [UniProtKB:Q13563] synonym: "polycystwin (human)" EXACT [UniProtKB:Q13563] synonym: "polycystic kidney disease 2 protein (human)" EXACT [UniProtKB:Q13563] synonym: "autosomal dominant polycystic kidney disease type II protein (human)" EXACT [UniProtKB:Q13563] synonym: "transient receptor potential cation channel subfamily P member 2 (human)" EXACT [UniProtKB:Q13563] xref: Reactome:R-HSA-5623393 "PR:Q13563 located_in GO:0000139" xref: Reactome:R-HSA-5623409 "PR:Q13563 located_in GO:0060170" xref: Reactome:R-HSA-5623411 "PR:Q13563 located_in GO:0030660" xref: DTO:01100280 xref: UniProtKB:Q13563 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012773 ! polycystin-2 relationship: has_gene_template HGNC:9009 ! PKD2 (human) [Term] id: PR:Q13563-3 name: polycystin-2 isoform h3 (human) def: "A polycystin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13563-3." [PRO:DNx, UniProtKB:Q13563] comment: Category=organism-sequence. synonym: "hPKD2/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta7 (human)" EXACT [UniProtKB:Q13563] xref: UniProtKB:Q13563-3 is_a: PR:Q13563 ! polycystin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13563-2 name: polycystin-2 isoform h2 (human) def: "A polycystin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13563-2." [PRO:DNx, UniProtKB:Q13563] comment: Category=organism-sequence. synonym: "hPKD2/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta6 (human)" EXACT [UniProtKB:Q13563] xref: UniProtKB:Q13563-2 is_a: PR:Q13563 ! polycystin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13563-1 name: polycystin-2 isoform h1 (human) def: "A polycystin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13563-1." [PRO:DNx, UniProtKB:Q13563] comment: Category=organism-sequence. synonym: "hPKD2/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q13563-1 is_a: PR:Q13563 ! polycystin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O35245 name: polycystin-2 (mouse) def: "A polycystin-2 that is encoded in the genome of mouse." [OMA:O35245, PRO:DNx] comment: Category=organism-gene. synonym: "Pkd2" RELATED Gene-based [UniProtKB:O35245] synonym: "TRPP2" RELATED Gene-based [UniProtKB:O35245] synonym: "mPKD2" EXACT PRO-short-label [PRO:DNx] synonym: "polycystic kidney disease 2 protein homolog (mouse)" EXACT [UniProtKB:O35245] synonym: "transient receptor potential cation channel subfamily P member 2 (mouse)" EXACT [UniProtKB:O35245] xref: UniProtKB:O35245 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012773 ! polycystin-2 relationship: has_gene_template MGI:1099818 ! Pkd2 (mouse) [Term] id: PR:Q13563-5 name: polycystin-2 isoform h5 (human) def: "A polycystin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13563-5." [PRO:DNx, UniProtKB:Q13563] comment: Category=organism-sequence. synonym: "hPKD2/iso:h5" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta12/13 (human)" EXACT [UniProtKB:Q13563] xref: UniProtKB:Q13563-5 is_a: PR:Q13563 ! polycystin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q13563-4 name: polycystin-2 isoform h4 (human) def: "A polycystin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13563-4." [PRO:DNx, UniProtKB:Q13563] comment: Category=organism-sequence. synonym: "hPKD2/iso:h4" EXACT PRO-short-label [PRO:DNx] synonym: "polycystin-2 isoform delta9 (human)" EXACT [UniProtKB:Q13563] xref: UniProtKB:Q13563-4 is_a: PR:Q13563 ! polycystin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000012773 name: polycystin-2 def: "A transient receptor potential channel protein that is a translation product of the human PKD2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PKD2" EXACT PRO-short-label [PRO:DNx] synonym: "TRPP2" RELATED Gene-based [] synonym: "R48321" EXACT [] synonym: "polycystwin" EXACT [] synonym: "polycystic kidney disease 2 protein" EXACT [] synonym: "polycystic kidney disease 2 protein homolog" EXACT [] synonym: "autosomal dominant polycystic kidney disease type II protein" EXACT [] synonym: "transient receptor potential cation channel subfamily P member 2" EXACT [] xref: IUPHARobj:504 is_a: PR:000044657 ! transient receptor potential channel protein [Term] id: PR:000045919 name: polycystin-2 phosphorylated 1 (human) def: "A polycystin-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-829 of the amino acid sequence represented by UniProtKB:Q13563-1. Example: UniProtKB:Q13563-1, Ser-829, MOD:00046." [PMID:23390129, iPTMnet:Q13563] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23390129). Status=unreviewed. synonym: "hPKD2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q13563-1, Ser-829, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q13563 ! polycystin-2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6IVV8 name: polycystin-2 (zebrafish) def: "A polycystin-2 that is encoded in the genome of zebrafish." [OMA:Q6IVV8, PRO:DNx] comment: Category=organism-gene. synonym: "pkd2" RELATED Gene-based [UniProtKB:Q6IVV8] synonym: "z-PKD2" EXACT PRO-short-label [PRO:DNx] synonym: "Cup (zebrafish)" EXACT [UniProtKB:Q6IVV8] synonym: "curly up (zebrafish)" EXACT [UniProtKB:Q6IVV8] synonym: "polycystic kidney disease 2 protein homolog (zebrafish)" EXACT [UniProtKB:Q6IVV8] synonym: "transient receptor potential cation channel subfamily P member 2 (zebrafish)" EXACT [UniProtKB:Q6IVV8] xref: UniProtKB:Q6IVV8 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000012773 ! polycystin-2 relationship: has_gene_template ZFIN:ZDB-GENE-040827-4 ! pkd2 (zebrafish)