[Term]
id: PR:000021079
name: peroxiredoxin-6, initiator methionine removed form
def: "A peroxiredoxin-6 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "PRDX6/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000013196 ! peroxiredoxin-6
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:O35244
name: peroxiredoxin-6 (rat)
def: "A peroxiredoxin-6 that is encoded in the genome of rat." [OMA:O35244, PANTHER:PTHR10681:SF17, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tsa" RELATED Gene-based [UniProtKB:O35244]
synonym: "Aop2" RELATED Gene-based [UniProtKB:O35244]
synonym: "Prdx6" RELATED Gene-based [UniProtKB:O35244]
synonym: "Aipla2" RELATED Gene-based [UniProtKB:O35244]
synonym: "rPRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "NSGPx (rat)" EXACT [UniProtKB:O35244]
synonym: "aiPLA2 (rat)" EXACT [UniProtKB:O35244]
synonym: "LPCAT-5 (rat)" EXACT [UniProtKB:O35244]
synonym: "1-Cys PRX (rat)" EXACT [UniProtKB:O35244]
synonym: "1-Cys peroxiredoxin (rat)" EXACT [UniProtKB:O35244]
synonym: "LPC acyltransferase 5 (rat)" EXACT [UniProtKB:O35244]
synonym: "antioxidant protein 2 (rat)" EXACT [UniProtKB:O35244]
synonym: "lyso-PC acyltransferase 5 (rat)" EXACT [UniProtKB:O35244]
synonym: "thiol-specific antioxidant protein (rat)" RELATED [UniProtKB:O35244]
synonym: "glutathione-dependent peroxiredoxin (rat)" EXACT [UniProtKB:O35244]
synonym: "non-selenium glutathione peroxidase (rat)" EXACT [UniProtKB:O35244]
synonym: "lysophosphatidylcholine acyltransferase 5 (rat)" EXACT [UniProtKB:O35244]
synonym: "acidic calcium-independent phospholipase A2 (rat)" EXACT [UniProtKB:O35244]
xref: UniProtKB:O35244
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template RGD:71005 ! Prdx6 (rat)

[Term]
id: PR:P34227
name: peroxiredoxin PRX1, mitochondrial (yeast)
def: "A peroxiredoxin-6 that is encoded in the genome of yeast." [OMA:P34227, PANTHER:PTHR10681:SF17, PRO:DNx]
comment: Category=organism-gene.
synonym: "PRX1" RELATED Gene-based [UniProtKB:P34227]
synonym: "yPRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "YBL0503" RELATED Gene-based [UniProtKB:P34227]
synonym: "YBL0524" RELATED Gene-based [UniProtKB:P34227]
synonym: "YBL064C" RELATED Gene-based [UniProtKB:P34227]
synonym: "Prx (yeast)" BROAD [UniProtKB:P34227]
synonym: "mTPx (yeast)" EXACT [UniProtKB:P34227]
synonym: "1-Cys PRX (yeast)" EXACT [UniProtKB:P34227]
synonym: "thioredoxin peroxidase (yeast)" RELATED [UniProtKB:P34227]
synonym: "mitochondrial thiol peroxidase (yeast)" EXACT [UniProtKB:P34227]
synonym: "glutathione-dependent peroxiredoxin (yeast)" EXACT [UniProtKB:P34227]
synonym: "glutaredoxin-dependent peroxiredoxin (yeast)" EXACT [UniProtKB:P34227]
xref: UniProtKB:P34227
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template SGD:S000000160 ! PRX1 (yeast)

[Term]
id: PR:Q5ZJF4
name: peroxiredoxin-6 (chicken)
def: "A peroxiredoxin-6 that is encoded in the genome of chicken." [PANTHER:PTHR10681:SF17, PRO:DNx]
comment: Category=organism-gene.
synonym: "PRDX6" RELATED Gene-based [UniProtKB:Q5ZJF4]
synonym: "chick-PRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_18k11" RELATED Gene-based [UniProtKB:Q5ZJF4]
synonym: "NSGPx (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "aiPLA2 (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "LPCAT-5 (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "1-Cys PRX (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "1-Cys peroxiredoxin (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "LPC acyltransferase 5 (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "lyso-PC acyltransferase 5 (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "glutathione-dependent peroxiredoxin (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "non-selenium glutathione peroxidase (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "lysophosphatidylcholine acyltransferase 5 (chicken)" EXACT [UniProtKB:Q5ZJF4]
synonym: "acidic calcium-independent phospholipase A2 (chicken)" EXACT [UniProtKB:Q5ZJF4]
xref: UniProtKB:Q5ZJF4
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template NCBIGene:429062 ! PRDX6 (chicken)

[Term]
id: PR:O08709-1
name: peroxiredoxin-6 isoform 1 (mouse)
def: "A peroxiredoxin-6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPRDX6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O08709-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039231 ! peroxiredoxin-6 isoform 1

[Term]
id: PR:P30041
name: peroxiredoxin-6 (human)
def: "A peroxiredoxin-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P30041]
comment: Category=organism-gene.
synonym: "AOP2" RELATED Gene-based [UniProtKB:P30041]
synonym: "PRDX6" RELATED Gene-based [UniProtKB:P30041]
synonym: "hPRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0106" RELATED Gene-based [UniProtKB:P30041]
synonym: "NSGPx (human)" EXACT [UniProtKB:P30041]
synonym: "aiPLA2 (human)" EXACT [UniProtKB:P30041]
synonym: "LPCAT-5 (human)" EXACT [UniProtKB:P30041]
synonym: "1-Cys PRX (human)" EXACT [UniProtKB:P30041]
synonym: "24 kDa protein (human)" EXACT [UniProtKB:P30041]
synonym: "1-Cys peroxiredoxin (human)" EXACT [UniProtKB:P30041]
synonym: "LPC acyltransferase 5 (human)" EXACT [UniProtKB:P30041]
synonym: "antioxidant protein 2 (human)" EXACT [UniProtKB:P30041]
synonym: "liver 2D page spot 40 (human)" EXACT [UniProtKB:P30041]
synonym: "lyso-PC acyltransferase 5 (human)" EXACT [UniProtKB:P30041]
synonym: "red blood cells page spot 12 (human)" EXACT [UniProtKB:P30041]
synonym: "glutathione-dependent peroxiredoxin (human)" EXACT [UniProtKB:P30041]
synonym: "non-selenium glutathione peroxidase (human)" EXACT [UniProtKB:P30041]
synonym: "lysophosphatidylcholine acyltransferase 5 (human)" EXACT [UniProtKB:P30041]
synonym: "acidic calcium-independent phospholipase A2 (human)" EXACT [UniProtKB:P30041]
xref: UniProtKB:P30041
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template HGNC:16753 ! PRDX6 (human)

[Term]
id: PR:Q54SE2
name: 1-Cys peroxiredoxin (Dictyostelium discoideum)
def: "A peroxiredoxin-6 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54SE2, PANTHER:PTHR10681:SF17, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-PRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0282517" RELATED Gene-based [UniProtKB:Q54SE2]
synonym: "thioredoxin peroxidase (Dictyostelium discoideum)" EXACT [UniProtKB:Q54SE2]
synonym: "thiol-specific antioxidant (Dictyostelium discoideum)" EXACT [UniProtKB:Q54SE2]
synonym: "thioredoxin-dependent peroxiredoxin (Dictyostelium discoideum)" EXACT [UniProtKB:Q54SE2]
xref: UniProtKB:Q54SE2
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template dictyBase:DDB_G0282517 ! DDB_G0282517 (Dictyostelium discoideum)

[Term]
id: PR:000048899
name: peroxiredoxin-6, initiator methionine removed form (human)
def: "A peroxiredoxin-6 (human) that has had the initiator methionine removed. UniProtKB:P30041, 2-224." [PRO:DNx, Reactome:R-HSA-3343670]
comment: Category=organism-modification.
synonym: "PRO_0000135102" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPRDX6/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P30041, 2-224" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3343670 "PR:000048899 located_in GO:0005829"
xref: Reactome:R-HSA-6806198 "PR:000048899 located_in GO:0005576"
xref: Reactome:R-HSA-6798744 "PR:000048899 located_in GO:0035578"
xref: TDR:1540
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P30041 ! peroxiredoxin-6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O04005
name: 1-Cys peroxiredoxin PER1 (Arabidopsis thaliana)
def: "A peroxiredoxin-6 that is encoded in the genome of Arabidopsis thaliana." [OMA:O04005, PANTHER:PTHR10681:SF17, PRO:DNx]
comment: Category=organism-gene.
synonym: "PER1" RELATED Gene-based [UniProtKB:O04005]
synonym: "At-PRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "At1g48130" RELATED Gene-based [UniProtKB:O04005]
synonym: "F21D18.15" RELATED Gene-based [UniProtKB:O04005]
synonym: "rehydrin homolog (Arabidopsis thaliana)" EXACT [UniProtKB:O04005]
synonym: "thioredoxin peroxidase (Arabidopsis thaliana)" RELATED [UniProtKB:O04005]
synonym: "thioredoxin-dependent peroxiredoxin (Arabidopsis thaliana)" EXACT [UniProtKB:O04005]
xref: UniProtKB:O04005
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template Araport:AT1G48130 ! PER1 (Arabidopsis thaliana)

[Term]
id: PR:000039231
name: peroxiredoxin-6 isoform 1
def: "A peroxiredoxin-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30041-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PRDX6/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013196 ! peroxiredoxin-6

[Term]
id: PR:O08709
name: peroxiredoxin-6 (mouse)
def: "A peroxiredoxin-6 that is encoded in the genome of mouse." [OMA:O08709, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aop2" RELATED Gene-based [UniProtKB:O08709]
synonym: "Ltw4" RELATED Gene-based [UniProtKB:O08709]
synonym: "Prdx5" RELATED Gene-based [UniProtKB:O08709]
synonym: "Prdx6" RELATED Gene-based [UniProtKB:O08709]
synonym: "mPRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "NSGPx (mouse)" EXACT [UniProtKB:O08709]
synonym: "aiPLA2 (mouse)" EXACT [UniProtKB:O08709]
synonym: "LPCAT-5 (mouse)" EXACT [UniProtKB:O08709]
synonym: "1-Cys PRX (mouse)" EXACT [UniProtKB:O08709]
synonym: "1-Cys peroxiredoxin (mouse)" EXACT [UniProtKB:O08709]
synonym: "LPC acyltransferase 5 (mouse)" EXACT [UniProtKB:O08709]
synonym: "antioxidant protein 2 (mouse)" EXACT [UniProtKB:O08709]
synonym: "lyso-PC acyltransferase 5 (mouse)" EXACT [UniProtKB:O08709]
synonym: "glutathione-dependent peroxiredoxin (mouse)" EXACT [UniProtKB:O08709]
synonym: "non-selenium glutathione peroxidase (mouse)" EXACT [UniProtKB:O08709]
synonym: "lysophosphatidylcholine acyltransferase 5 (mouse)" EXACT [UniProtKB:O08709]
synonym: "acidic calcium-independent phospholipase A2 (mouse)" EXACT [UniProtKB:O08709]
xref: UniProtKB:O08709
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013196 ! peroxiredoxin-6
relationship: has_gene_template MGI:894320 ! Prdx6 (mouse)

[Term]
id: PR:000013196
name: peroxiredoxin-6
def: "A protein that is a translation product of the human PRDX6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AOP2" RELATED Gene-based []
synonym: "Ltw4" RELATED Gene-based []
synonym: "NSGPx" EXACT []
synonym: "PRDX6" EXACT PRO-short-label [PRO:DNx]
synonym: "Prdx5" RELATED Gene-based []
synonym: "aiPLA2" EXACT []
synonym: "LPCAT-5" EXACT []
synonym: "KIAA0106" RELATED Gene-based []
synonym: "1-Cys PRX" EXACT []
synonym: "24 kDa protein" EXACT []
synonym: "1-Cys peroxiredoxin" EXACT []
synonym: "LPC acyltransferase 5" EXACT []
synonym: "antioxidant protein 2" EXACT []
synonym: "liver 2D page spot 40" EXACT []
synonym: "lyso-PC acyltransferase 5" EXACT []
synonym: "red blood cells page spot 12" EXACT []
synonym: "glutathione-dependent peroxiredoxin" EXACT []
synonym: "non-selenium glutathione peroxidase" EXACT []
synonym: "lysophosphatidylcholine acyltransferase 5" EXACT []
synonym: "acidic calcium-independent phospholipase A2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P30041-1
name: peroxiredoxin-6 isoform 1 (human)
def: "A peroxiredoxin-6 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPRDX6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P30041-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039231 ! peroxiredoxin-6 isoform 1

[Term]
id: PR:O35244-1
name: peroxiredoxin-6 isoform 1 (rat)
def: "A peroxiredoxin-6 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rPRDX6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O35244-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039231 ! peroxiredoxin-6 isoform 1