[Term] id: PR:000046132 name: cAMP-dependent protein kinase regulatory subunit phosphorylated 1 (yeast) def: "A cAMP-dependent protein kinase regulatory subunit (yeast) that has been phosphorylated at Ser-145. UniProtKB:P07278, Ser-145, MOD:00046." [PMID:20826609, iPTMnet:P07278] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20826609). Status=unreviewed. synonym: "yPRKAR2A/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P07278, Ser-145, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P07278 ! cAMP-dependent protein kinase regulatory subunit (yeast) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C [Term] id: PR:P07278 name: cAMP-dependent protein kinase regulatory subunit (yeast) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of yeast." [OMA:P07278, PRO:DNx] comment: Category=organism-gene. synonym: "BCY1" RELATED Gene-based [UniProtKB:P07278] synonym: "REG1" RELATED Gene-based [UniProtKB:P07278] synonym: "SRA1" RELATED Gene-based [UniProtKB:P07278] synonym: "YIL033C" RELATED Gene-based [UniProtKB:P07278] synonym: "yPRKAR2A" EXACT PRO-short-label [PRO:DNx] synonym: "PKA regulatory subunit (yeast)" EXACT [UniProtKB:P07278] synonym: "cAPK regulatory subunit (yeast)" EXACT [UniProtKB:P07278] synonym: "protein kinase A regulatory subunit (yeast)" EXACT [UniProtKB:P07278] synonym: "bypass of cyclase mutations protein 1 (yeast)" EXACT [UniProtKB:P07278] xref: UniProtKB:P07278 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000013230 ! cAMP-dependent protein kinase type II-alpha regulatory subunit relationship: has_gene_template SGD:S000001295 ! BCY1 (yeast) [Term] id: PR:P13861 name: cAMP-dependent protein kinase type II-alpha regulatory subunit (human) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:P13861] comment: Category=organism-gene. synonym: "PKR2" RELATED Gene-based [UniProtKB:P13861] synonym: "PRKAR2" RELATED Gene-based [UniProtKB:P13861] synonym: "PRKAR2A" RELATED Gene-based [UniProtKB:P13861] synonym: "hPRKAR2A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P13861 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013230 ! cAMP-dependent protein kinase type II-alpha regulatory subunit relationship: has_gene_template HGNC:9391 ! PRKAR2A (human) [Term] id: PR:000021090 name: cAMP-dependent protein kinase type II-alpha regulatory subunit, initiator methionine removed form def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit that has had the initiator methionine removed." [PRO:DNx] comment: Category=modification. synonym: "PRKAR2A/InitMet-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000013230 ! cAMP-dependent protein kinase type II-alpha regulatory subunit intersection_of: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P00515 name: cAMP-dependent protein kinase type II-alpha regulatory subunit (cow) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of cow." [OMA:P00515, PRO:DNx] comment: Category=organism-gene. Requested by=PubChem. synonym: "PRKAR2A" RELATED Gene-based [UniProtKB:P00515] synonym: "cow-PRKAR2A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P00515 intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus intersection_of: PR:000013230 ! cAMP-dependent protein kinase type II-alpha regulatory subunit relationship: has_gene_template NCBIGene:100139910 ! PRKAR2A (cow) [Term] id: PR:P12368 name: cAMP-dependent protein kinase type II-alpha regulatory subunit (rat) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of rat." [OMA:P12368, PANTHER:PTHR11635:SF18, PRO:DNx] comment: Category=organism-gene. synonym: "Prkar2a" RELATED Gene-based [UniProtKB:P12368] synonym: "rPRKAR2A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12368 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000013230 ! cAMP-dependent protein kinase type II-alpha regulatory subunit relationship: has_gene_template RGD:3393 ! Prkar2a (rat) [Term] id: PR:P12367 name: cAMP-dependent protein kinase type II-alpha regulatory subunit (mouse) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of mouse." [OMA:P12367, PRO:DNx] comment: Category=organism-gene. synonym: "Prkar2a" RELATED Gene-based [UniProtKB:P12367] synonym: "mPRKAR2A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P12367 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000013230 ! cAMP-dependent protein kinase type II-alpha regulatory subunit relationship: has_gene_template MGI:108025 ! Prkar2a (mouse) [Term] id: PR:P13861-2 name: cAMP-dependent protein kinase type II-alpha regulatory subunit isoform h2 (human) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13861-2." [PRO:DNx, UniProtKB:P13861] comment: Category=organism-sequence. synonym: "hPRKAR2A/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P13861-2 is_a: PR:P13861 ! cAMP-dependent protein kinase type II-alpha regulatory subunit (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P13861-1 name: cAMP-dependent protein kinase type II-alpha regulatory subunit isoform h1 (human) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13861-1." [PRO:DNx, UniProtKB:P13861] comment: Category=organism-sequence. synonym: "hPRKAR2A/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P13861-1 is_a: PR:P13861 ! cAMP-dependent protein kinase type II-alpha regulatory subunit (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048908 name: cAMP-dependent protein kinase type II-alpha regulatory subunit, initiator methionine removed form (human) def: "A cAMP-dependent protein kinase type II-alpha regulatory subunit (human) that has had the initiator methionine removed. UniProtKB:P13861, 2-404." [PRO:DNx, Reactome:R-HSA-5610412, Reactome:R-HSA-57840] comment: Category=organism-modification. synonym: "PRO_0000205385" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPRKAR2A/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P13861, 2-404" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-57840 "PR:000048908 located_in GO:0005829" xref: Reactome:R-HSA-5610412 "PR:000048908 located_in GO:0097546" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P13861 ! cAMP-dependent protein kinase type II-alpha regulatory subunit (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000013230 name: cAMP-dependent protein kinase type II-alpha regulatory subunit def: "A protein that is a translation product of the human PRKAR2A gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PKR2" RELATED Gene-based [] synonym: "PRKAR2" RELATED Gene-based [] synonym: "PRKAR2A" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1474 is_a: PR:000000001 ! protein