[Term] id: PR:Q05513-1 name: protein kinase C zeta type isoform 1 (human) def: "A protein kinase C zeta type isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPRKCZ/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q05513-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040284 ! protein kinase C zeta type isoform 1 [Term] id: PR:Q05513-3 name: protein kinase C zeta type isoform h3 (human) def: "A protein kinase C zeta type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05513-3." [PRO:DNx, UniProtKB:Q05513] comment: Category=organism-sequence. synonym: "hPRKCZ/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q05513-3 is_a: PR:Q05513 ! protein kinase C zeta type (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q05513-2 name: protein kinase C zeta type isoform h2 (human) def: "A protein kinase C zeta type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05513-2." [PRO:DNx, UniProtKB:Q05513] comment: Category=organism-sequence. synonym: "hPRKCZ/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "protein kinase C zeta type isoform PKMzeta (human)" EXACT [UniProtKB:Q05513] xref: UniProtKB:Q05513-2 is_a: PR:Q05513 ! protein kinase C zeta type (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045879 name: protein kinase C zeta type phosphorylated 1 (human) def: "A protein kinase C zeta type (human) that has been phosphorylated on the residue at the position equivalent to Thr-410 of the amino acid sequence represented by UniProtKB:Q05513-1. Example: UniProtKB:Q05513-1, Thr-410, MOD:00047." [PMID:11222751, PMID:12887331, PMID:15314172, PMID:17335005, PMID:9768361, iPTMnet:Q05513] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11222751, PMID:12887331, PMID:15314172, PMID:17335005, PMID:9768361). Status=unreviewed. synonym: "hPRKCZ/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q05513-1, Thr-410, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-437181 "PR:000045879 located_in GO:0005829" is_a: PR:Q05513 ! protein kinase C zeta type (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q05513 name: protein kinase C zeta type (human) def: "A protein kinase C zeta type that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q05513] comment: Category=organism-gene. synonym: "PKC2" RELATED Gene-based [UniProtKB:Q05513] synonym: "PRKCZ" RELATED Gene-based [UniProtKB:Q05513] synonym: "hPRKCZ" EXACT PRO-short-label [PRO:DNx] synonym: "nPKC-zeta (human)" EXACT [UniProtKB:Q05513] xref: Reactome:R-HSA-58218 "PR:Q05513 located_in GO:0005829" xref: Reactome:R-HSA-2134483 "PR:Q05513 located_in GO:0030054" xref: DTO:03100247 xref: UniProtKB:Q05513 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013235 ! protein kinase C zeta type relationship: has_gene_template HGNC:9412 ! PRKCZ (human) [Term] id: PR:000013235 name: protein kinase C zeta type def: "A protein kinase C, iota-like that is a translation product of the human PRKCZ gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PKC2" RELATED Gene-based [] synonym: "Pkcz" RELATED Gene-based [] synonym: "PRKCZ" EXACT PRO-short-label [PRO:DNx] synonym: "nPKC-zeta" EXACT [] xref: IUPHARobj:1491 is_a: PR:000045383 ! protein kinase C, iota-like [Term] id: PR:000048924 name: protein kinase C zeta type phosphorylated 2 (human) def: "A protein kinase C zeta type (human) that has been post-translationally modified to include phosphothreonine at positions 410 and 560 of the amino acid sequence represented by UniProtKB:Q05513. UniProtKB:Q05513, Thr-410/Thr-560, MOD:00047." [PRO:DNx, Reactome:R-HSA-5218698] comment: Category=organism-modification. synonym: "hPRKCZ/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q05513, Thr-410/Thr-560, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5218698 "PR:000048924 located_in GO:0005829" is_a: PR:Q05513 ! protein kinase C zeta type (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens