[Term]
id: PR:000013346
name: gamma-secretase subunit PEN-2
def: "A protein that is a translation product of the human PSENEN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=Alzforum.
synonym: "PEN2" RELATED Gene-based []
synonym: "MDS033" RELATED Gene-based []
synonym: "PSENEN" EXACT PRO-short-label [PRO:DNx]
synonym: "presenilin enhancer protein 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9CQR7
name: gamma-secretase subunit PEN-2 (mouse)
def: "A gamma-secretase subunit PEN-2 that is encoded in the genome of mouse." [OMA:Q9CQR7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pen2" RELATED Gene-based [UniProtKB:Q9CQR7]
synonym: "Psenen" RELATED Gene-based [UniProtKB:Q9CQR7]
synonym: "mPSENEN" EXACT PRO-short-label [PRO:DNx]
synonym: "presenilin enhancer protein 2 (mouse)" EXACT [UniProtKB:Q9CQR7]
xref: UniProtKB:Q9CQR7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013346 ! gamma-secretase subunit PEN-2
relationship: has_gene_template MGI:1913590 ! Psenen (mouse)

[Term]
id: PR:Q9CQR7-1
name: gamma-secretase subunit PEN-2 isoform 1 (mouse)
def: "A gamma-secretase subunit PEN-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPSENEN/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9CQR7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000043676 ! gamma-secretase subunit PEN-2 isoform 1

[Term]
id: PR:000036245
name: gamma-secretase subunit PEN-2 acetylated 1 (mouse)
def: "A gamma-secretase subunit PEN-2 (mouse) that is N-terminal Met acetylated. UniProtKB:Q9CQR7, Met-1, MOD:00058." [TDR:8786]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "mPSENEN/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9CQR7, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:8786
is_a: PR:Q9CQR7 ! gamma-secretase subunit PEN-2 (mouse)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus