[Term]
id: PR:000013457
name: tyrosine-protein phosphatase non-receptor type 22
def: "A protein that is a translation product of the human PTPN22 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LyP" EXACT []
synonym: "PEP" EXACT []
synonym: "PTPN8" RELATED Gene-based []
synonym: "PTPN22" EXACT PRO-short-label [PRO:DNx]
synonym: "lymphoid phosphatase" EXACT []
synonym: "PEST-domain phosphatase" EXACT []
synonym: "hematopoietic cell protein-tyrosine phosphatase 70Z-PEP" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P29352
name: tyrosine-protein phosphatase non-receptor type 22 (mouse)
def: "A tyrosine-protein phosphatase non-receptor type 22 that is encoded in the genome of mouse." [OMA:P29352, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ptpn8" RELATED Gene-based [UniProtKB:P29352]
synonym: "Ptpn22" RELATED Gene-based [UniProtKB:P29352]
synonym: "mPTPN22" EXACT PRO-short-label [PRO:DNx]
synonym: "PEP (mouse)" EXACT [UniProtKB:P29352]
synonym: "PEST-domain phosphatase (mouse)" EXACT [UniProtKB:P29352]
synonym: "hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (mouse)" EXACT [UniProtKB:P29352]
xref: UniProtKB:P29352
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013457 ! tyrosine-protein phosphatase non-receptor type 22
relationship: has_gene_template MGI:107170 ! Ptpn22 (mouse)

[Term]
id: PR:Q9Y2R2-6
name: tyrosine-protein phosphatase non-receptor type 22 isoform h6 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2R2-6." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-sequence.
synonym: "hPTPN22/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 22 isoform PTPN22.6 (human)" EXACT [UniProtKB:Q9Y2R2]
xref: UniProtKB:Q9Y2R2-6
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y2R2-5
name: tyrosine-protein phosphatase non-receptor type 22 isoform h5 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2R2-5." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-sequence.
synonym: "hPTPN22/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y2R2-5
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y2R2-4
name: tyrosine-protein phosphatase non-receptor type 22 isoform h4 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2R2-4." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-sequence.
synonym: "hPTPN22/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 22 isoform LYP3 (human)" EXACT [UniProtKB:Q9Y2R2]
xref: UniProtKB:Q9Y2R2-4
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y2R2-3
name: tyrosine-protein phosphatase non-receptor type 22 isoform h3 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2R2-3." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-sequence.
synonym: "hPTPN22/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y2R2-3
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y2R2-2
name: tyrosine-protein phosphatase non-receptor type 22 isoform h2 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2R2-2." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-sequence.
synonym: "hPTPN22/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 22 isoform LyP2 (human)" EXACT [UniProtKB:Q9Y2R2]
xref: UniProtKB:Q9Y2R2-2
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y2R2-1
name: tyrosine-protein phosphatase non-receptor type 22 isoform 1 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2R2-1." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hPTPN22/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "tyrosine-protein phosphatase non-receptor type 22 isoform LyP1 (human)" EXACT [UniProtKB:Q9Y2R2]
xref: UniProtKB:Q9Y2R2-1
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046098
name: tyrosine-protein phosphatase non-receptor type 22 phosphorylated 1 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 (human) that has been phosphorylated on the residue at the position equivalent to Ser-35 of the amino acid sequence represented by UniProtKB:Q9Y2R2-1. Example: UniProtKB:Q9Y2R2-1, Ser-35, MOD:00046." [PMID:18056643, iPTMnet:Q9Y2R2]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18056643). Status=unreviewed.
synonym: "hPTPN22/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y2R2-1, Ser-35, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9Y2R2 ! tyrosine-protein phosphatase non-receptor type 22 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y2R2
name: tyrosine-protein phosphatase non-receptor type 22 (human)
def: "A tyrosine-protein phosphatase non-receptor type 22 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y2R2]
comment: Category=organism-gene.
synonym: "PTPN8" RELATED Gene-based [UniProtKB:Q9Y2R2]
synonym: "PTPN22" RELATED Gene-based [UniProtKB:Q9Y2R2]
synonym: "hPTPN22" EXACT PRO-short-label [PRO:DNx]
synonym: "LyP (human)" EXACT [UniProtKB:Q9Y2R2]
synonym: "PEP (human)" EXACT [UniProtKB:Q9Y2R2]
synonym: "lymphoid phosphatase (human)" EXACT [UniProtKB:Q9Y2R2]
synonym: "PEST-domain phosphatase (human)" EXACT [UniProtKB:Q9Y2R2]
synonym: "hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (human)" EXACT [UniProtKB:Q9Y2R2]
xref: Reactome:R-HSA-8852205 "PR:Q9Y2R2 located_in GO:0005829"
xref: UniProtKB:Q9Y2R2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013457 ! tyrosine-protein phosphatase non-receptor type 22
relationship: has_gene_template HGNC:9652 ! PTPN22 (human)