[Term]
id: PR:000013922
name: E3 ubiquitin-protein ligase COP1
def: "A protein that is a translation product of the human COP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "COP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RFWD2" RELATED Gene-based []
synonym: "RNF200" RELATED Gene-based []
synonym: "RING finger protein 200" EXACT []
synonym: "E3 ubiquitin-protein ligase RFWD2" EXACT []
synonym: "RING-type E3 ubiquitin transferase RFWD2" EXACT []
synonym: "RING finger and WD repeat domain protein 2" EXACT []
synonym: "constitutive photomorphogenesis protein 1 homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8NHY2-4
name: E3 ubiquitin-protein ligase COP1 isoform h4 (human)
def: "An E3 ubiquitin-protein ligase COP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NHY2-4." [PRO:DNx, UniProtKB:Q8NHY2]
comment: Category=organism-sequence.
synonym: "hCOP1/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "E3 ubiquitin-protein ligase COP1 isoform COP1D (human)" EXACT [UniProtKB:Q8NHY2]
xref: UniProtKB:Q8NHY2-4
is_a: PR:Q8NHY2 ! E3 ubiquitin-protein ligase COP1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8NHY2-1
name: E3 ubiquitin-protein ligase COP1 isoform 1 (human)
def: "An E3 ubiquitin-protein ligase COP1 isoform 1 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "hCOP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8NHY2-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026844 ! E3 ubiquitin-protein ligase COP1 isoform 1

[Term]
id: PR:Q8NHY2-2
name: E3 ubiquitin-protein ligase COP1 isoform h2 (human)
def: "An E3 ubiquitin-protein ligase COP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NHY2-2." [PRO:DNx, UniProtKB:Q8NHY2]
comment: Category=organism-sequence.
synonym: "hCOP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "E3 ubiquitin-protein ligase COP1 isoform delta24 (human)" EXACT [UniProtKB:Q8NHY2]
xref: UniProtKB:Q8NHY2-2
is_a: PR:Q8NHY2 ! E3 ubiquitin-protein ligase COP1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8NHY2-3
name: E3 ubiquitin-protein ligase COP1 isoform h3 (human)
def: "An E3 ubiquitin-protein ligase COP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NHY2-3." [PRO:DNx, UniProtKB:Q8NHY2]
comment: Category=organism-sequence.
synonym: "hCOP1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8NHY2-3
is_a: PR:Q8NHY2 ! E3 ubiquitin-protein ligase COP1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000026848
name: E3 ubiquitin-protein ligase COP1 phosphorylated 1 (human)
def: "An E3 ubiquitin-protein ligase COP1 phosphorylated 1 in human. Example: UniProtKB:Q8NHY2-1, Ser-387, MOD:00046." [PMID:20843328, PRO:CNx, Reactome:R-HSA-349439, Reactome:R-HSA-349450]
comment: Category=organism-modification.
synonym: "hCOP1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "phospho-COP1(Ser 387) (human)" EXACT [Reactome:R-HSA-349439, Reactome:R-HSA-349450]
synonym: "UniProtKB:Q8NHY2-1, Ser-387, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-349439 "PR:000026848 located_in GO:0005829"
xref: Reactome:R-HSA-349450 "PR:000026848 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026847 ! E3 ubiquitin-protein ligase COP1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:Q8NHY2-5
name: E3 ubiquitin-protein ligase COP1 isoform h5 (human)
def: "An E3 ubiquitin-protein ligase COP1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NHY2-5." [PRO:DNx, UniProtKB:Q8NHY2]
comment: Category=organism-sequence.
synonym: "hCOP1/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "E3 ubiquitin-protein ligase COP1 isoform E (human)" EXACT [UniProtKB:Q8NHY2]
xref: UniProtKB:Q8NHY2-5
is_a: PR:Q8NHY2 ! E3 ubiquitin-protein ligase COP1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8NHY2
name: E3 ubiquitin-protein ligase COP1 (human)
def: "An E3 ubiquitin-protein ligase COP1 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-gene.
synonym: "COP1" RELATED Gene-based [UniProtKB:Q8NHY2]
synonym: "RFWD2" RELATED Gene-based [UniProtKB:Q8NHY2]
synonym: "hCOP1" EXACT PRO-short-label [PRO:DNx]
synonym: "RNF200" RELATED Gene-based [UniProtKB:Q8NHY2]
synonym: "RING finger protein 200 (human)" EXACT [UniProtKB:Q8NHY2]
synonym: "RING-type E3 ubiquitin transferase RFWD2 (human)" EXACT [UniProtKB:Q8NHY2]
synonym: "RING finger and WD repeat domain protein 2 (human)" EXACT [UniProtKB:Q8NHY2]
synonym: "constitutive photomorphogenesis protein 1 homolog (human)" EXACT [UniProtKB:Q8NHY2]
xref: Reactome:R-HSA-349454 "PR:Q8NHY2 located_in GO:0005654"
xref: UniProtKB:Q8NHY2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013922 ! E3 ubiquitin-protein ligase COP1
relationship: has_gene_template HGNC:17440 ! COP1 (human)