[Term]
id: PR:000014153
name: roundabout homolog 3
def: "A ROBO protein that is a translation product of the human ROBO3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ROBO3" EXACT PRO-short-label [PRO:DNx]
synonym: "Rbig1" RELATED Gene-based []
synonym: "Rig-1" EXACT []
synonym: "roundabout-like protein 3" EXACT []
synonym: "retinoblastoma-inhibiting gene 1 protein" EXACT []
is_a: PR:000050051 ! ROBO protein

[Term]
id: PR:D3Z4M6
name: roundabout homolog 3 isoform ROBO3A.1 (mouse)
def: "A roundabout homolog 3 isoform ROBO3A.1 that is encoded in the genome of mouse. This isoform has a longer N-terminal sequence in comparison with ROBO3B isoforms and the C-terminal sequence arises from splicing of exon 26 to exon 27 and then to exon 28, with the resulting 78 amino acid peptide highly enriched in arginine/serine dipeptide repeats." [PMID:16226035, PRO:KRC, UniProtKB:D3Z4M6]
comment: Category=organism-sequence.
synonym: "mROBO3A" RELATED [PMID:16226035]
synonym: "mROBO3.1" RELATED [PMID:18466743]
synonym: "mRobo3A.1" EXACT [PRO:KRC]
synonym: "mROBO3/iso:ROBO3A1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:D3Z4M6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037773 ! roundabout homolog 3 isoform ROBO3A.1

[Term]
id: PR:Q9Z2I4
name: roundabout homolog 3 (mouse)
def: "A roundabout homolog 3 that is encoded in the genome of mouse." [OMA:Q9Z2I4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Rbig1" RELATED Gene-based [UniProtKB:Q9Z2I4]
synonym: "Robo3" RELATED Gene-based [UniProtKB:Q9Z2I4]
synonym: "mROBO3" EXACT PRO-short-label [PRO:DNx]
synonym: "Rig-1 (mouse)" EXACT [UniProtKB:Q9Z2I4]
synonym: "retinoblastoma-inhibiting gene 1 protein (mouse)" EXACT [UniProtKB:Q9Z2I4]
xref: UniProtKB:Q9Z2I4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014153 ! roundabout homolog 3
relationship: has_gene_template MGI:1343102 ! Robo3 (mouse)

[Term]
id: PR:E9QPQ1
name: roundabout homolog 3 isoform ROBO3B.1 (mouse)
def: "A roundabout homolog 3 isoform ROBO3B.1 that is encoded in the genome of mouse. This isoform has a shorter N-terminal sequence in comparison with ROBO3A isoforms and the C-terminal sequence arises from splicing of exon 26 to exon 27 and then to exon 28, with the resulting 78 amino acid peptide highly enriched in arginine/serine dipeptide repeats." [PMID:16554811, PMID:18466743, PRO:KRC]
comment: Category=organism-sequence.
synonym: "mROBO3B" RELATED [PMID:16226035]
synonym: "mROBO3.1" RELATED [PMID:18466743]
synonym: "mRobo3B.1" EXACT [PRO:KRC]
synonym: "mROBO3/iso:B1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:E9QPQ1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037774 ! roundabout homolog 3 isoform ROBO3B.1

[Term]
id: PR:F5GWJ5
name: roundabout homolog 3 isoform ROBO3B.1 (human)
def: "A roundabout homolog 3 isoform ROBO3B.1 that is encoded in the genome of human." [PMID:16554811, PMID:19690332, PRO:CNA, UniProtKB:F5GWJ5]
comment: Category=organism-sequence.
synonym: "hRobo3B" RELATED []
synonym: "hRobo3.1" RELATED []
synonym: "hRobo3B.1" EXACT [PRO:CNA]
synonym: "hROBO3/iso:ROBO3B.1" EXACT PRO-short-label [PRO:DNx]
synonym: "roundabout homolog 3 isoform 1" RELATED Gene-based [UniProtKB:Q96MS0]
xref: UniProtKB:F5GWJ5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037774 ! roundabout homolog 3 isoform ROBO3B.1

[Term]
id: PR:Q96MS0-1
name: roundabout homolog 3 isoform ROBO3A.1 (human)
def: "A roundabout homolog 3 isoform ROBO3A.1 that is encoded in the genome of human." [PMID:15105459, PRO:CNA, UniProtKB:Q96MS0]
comment: Category=organism-sequence.
synonym: "hRobo3A" RELATED []
synonym: "hRobo3.1" RELATED []
synonym: "hRobo3A.1" EXACT [PRO:CNA]
synonym: "hROBO3/iso:ROBO3A.1" EXACT PRO-short-label [PRO:DNx]
synonym: "roundabout homolog 3 isoform 1" RELATED Gene-based [UniProtKB:Q96MS0]
xref: UniProtKB:Q96MS0-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037773 ! roundabout homolog 3 isoform ROBO3A.1

[Term]
id: PR:Q96MS0-2
name: roundabout homolog 3 isoform h2 (human)
def: "A roundabout homolog 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96MS0-2." [PRO:DNx, UniProtKB:Q96MS0]
comment: Category=organism-sequence.
synonym: "hROBO3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96MS0-2
is_a: PR:Q96MS0 ! roundabout homolog 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Z2I4-2
name: roundabout homolog 3 isoform ROBO3B.2 (mouse)
def: "A roundabout homolog 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z2I4-2. Isoforms ROBO3B have a shorter N-terminal sequence than isoforms ROBO3A. Isoforms ROBO3.2 have a unique C-terminal sequence due to retention of the intron between exons 26 and 27." [PMID:10049565, PMID:16226035, PMID:18466743, PRO:KRC, UniProtKB:Q9Z2I4]
comment: Category=organism-sequence.
synonym: "mROBO3B" RELATED [PMID:16226035]
synonym: "mROBO3.2" RELATED [PMID:18466743]
synonym: "mRobo3B.2" EXACT [PRO:KRC]
synonym: "mROBO3/iso:ROBO3B.2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z2I4-2
is_a: PR:Q9Z2I4 ! roundabout homolog 3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9Z2I4-1
name: roundabout homolog 3 isoform ROBO3A.2 (mouse)
def: "A roundabout homolog 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z2I4-1. Isoforms ROBO3A have a longer N-terminal sequence than isoforms ROBO3B. Isoforms ROBO3.2 have a unique C-terminal sequence due to retention of the intron between exons 26 and 27." [PMID:16226035, PMID:18466743, PRO:KRC, UniProtKB:Q9Z2I4]
comment: Category=organism-sequence.
synonym: "mROBO3A" RELATED [PMID:16226035]
synonym: "mROBO3.2" RELATED [PMID:18466743]
synonym: "mRobo3A.2" EXACT [PRO:KRC]
synonym: "mROBO3/iso:ROBO3A.2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z2I4-1
is_a: PR:Q9Z2I4 ! roundabout homolog 3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037773
name: roundabout homolog 3 isoform ROBO3A.1
def: "A roundabout homolog 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96MS0-1 or a 1:1 ortholog thereof. Isoforms ROBO3A have a longer N-terminal sequence than isoforms ROBO3B. Isoforms ROBO3.1 have a C-terminal sequence highly enriched in arginine/serine dipeptide repeats." [PMID:15105459, PMID:16226035, PMID:18466743, PRO:CNA]
comment: Category=sequence.
synonym: "Robo3A.1" EXACT []
synonym: "ROBO3/iso:ROBO3A.1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014153 ! roundabout homolog 3

[Term]
id: PR:000037774
name: roundabout homolog 3 isoform ROBO3B.1
def: "A roundabout homolog 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E9QPQ1 or a 1:1 ortholog thereof. Isoforms ROBO3B have a shorter N-terminal sequence than isoforms ROBO3A. Isoforms ROBO3.1 have a C-terminal sequence highly enriched in arginine/serine dipeptide repeats." [PMID:18466743, PRO:CNA]
comment: Category=sequence.
synonym: "Robo3B.1" EXACT []
synonym: "ROBO3/iso:ROBO3B.1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014153 ! roundabout homolog 3

[Term]
id: PR:000037775
name: roundabout homolog 3 isoform ROBO3A (mouse)
def: "A roundabout homolog 3 (mouse) that has a longer N-terminal sequence than ROBO3B forms." [PMID:16226035, PMID:18466743, PRO:CNA]
comment: Category=union.
synonym: "Robo3A" EXACT []
synonym: "mROBO3/iso:ROBO3A[1/2]" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q9Z2I4 ! roundabout homolog 3 (mouse)
union_of: PR:D3Z4M6 ! roundabout homolog 3 isoform ROBO3A.1 (mouse)
union_of: PR:Q9Z2I4-1 ! roundabout homolog 3 isoform ROBO3A.2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037776
name: roundabout homolog 3 isoform ROBO3B (mouse)
def: "A roundabout homolog 3 (mouse) that has a shorter N-terminal sequence than ROBO3A forms." [PMID:16226035, PMID:18466743, PRO:CNA]
comment: Category=union.
synonym: "Robo3B" EXACT []
synonym: "mROBO3/iso:ROBO3B[1/2]" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q9Z2I4 ! roundabout homolog 3 (mouse)
union_of: PR:E9QPQ1 ! roundabout homolog 3 isoform ROBO3B.1 (mouse)
union_of: PR:Q9Z2I4-2 ! roundabout homolog 3 isoform ROBO3B.2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037777
name: roundabout homolog 3 isoform ROBO3.1 (mouse)
def: "A roundabout homolog 3 (mouse) that has a C-terminal sequence that includes the region encoded by exons 26, 27 and 28. The resulting 78 amino acid peptide is highly enriched in arginine/serine dipeptide repeats." [PMID:16554811, PMID:18466743, PRO:KRC]
comment: Category=union.
synonym: "Robo3.1" EXACT []
synonym: "mROBO3/iso:ROBO3[A/B]1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q9Z2I4 ! roundabout homolog 3 (mouse)
union_of: PR:D3Z4M6 ! roundabout homolog 3 isoform ROBO3A.1 (mouse)
union_of: PR:E9QPQ1 ! roundabout homolog 3 isoform ROBO3B.1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037778
name: roundabout homolog 3 isoform ROBO3.2 (mouse)
def: "A roundabout homolog 3 (mouse) that has a unique C-terminal sequence due to retention of the intron between exons 26 and 27." [PMID:16554811, PMID:18466743, PRO:KRC]
comment: Category=union.
synonym: "Robo3.2" EXACT []
synonym: "mROBO3/iso:ROBO3[A/B]2" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q9Z2I4 ! roundabout homolog 3 (mouse)
union_of: PR:Q9Z2I4-1 ! roundabout homolog 3 isoform ROBO3A.2 (mouse)
union_of: PR:Q9Z2I4-2 ! roundabout homolog 3 isoform ROBO3B.2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q96MS0
name: roundabout homolog 3 (human)
def: "A roundabout homolog 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96MS0]
comment: Category=organism-gene.
synonym: "ROBO3" RELATED Gene-based [UniProtKB:Q96MS0]
synonym: "hROBO3" EXACT PRO-short-label [PRO:DNx]
synonym: "roundabout-like protein 3 (human)" EXACT [UniProtKB:Q96MS0]
xref: UniProtKB:Q96MS0
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014153 ! roundabout homolog 3
relationship: has_gene_template HGNC:13433 ! ROBO3 (human)