[Term]
id: PR:000046102
name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 phosphorylated 1 (human)
def: "A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-592 of the amino acid sequence represented by UniProtKB:Q9Y3Z3-1. Example: UniProtKB:Q9Y3Z3-1, Thr-592, MOD:00047." [PMID:23602554, iPTMnet:Q9Y3Z3]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23602554). Status=unreviewed.
synonym: "hSAMHD1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y3Z3-1, Thr-592, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9Y3Z3 ! deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000014443
name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1
def: "A protein that is a translation product of the human SAMHD1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DCIP" EXACT []
synonym: "MOP5" RELATED Gene-based []
synonym: "Mg11" RELATED []
synonym: "MOP-5" EXACT []
synonym: "SAMHD1" EXACT PRO-short-label [PRO:DNx]
synonym: "dNTPase" EXACT []
synonym: "monocyte protein 5" EXACT []
synonym: "interferon-gamma-inducible protein Mg11" EXACT []
synonym: "dendritic cell-derived IFNG-induced protein" EXACT []
synonym: "SAM domain and HD domain-containing protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9Y3Z3-3
name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform h3 (human)
def: "A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y3Z3-3." [PRO:DNx, UniProtKB:Q9Y3Z3]
comment: Category=organism-sequence.
synonym: "hSAMHD1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform delta8-9 (human)" EXACT [UniProtKB:Q9Y3Z3]
xref: UniProtKB:Q9Y3Z3-3
is_a: PR:Q9Y3Z3 ! deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y3Z3-1
name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform h1 (human)
def: "A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y3Z3-1." [PRO:DNx, UniProtKB:Q9Y3Z3]
comment: Category=organism-sequence.
synonym: "hSAMHD1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y3Z3-1
is_a: PR:Q9Y3Z3 ! deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y3Z3
name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human)
def: "A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y3Z3]
comment: Category=organism-gene.
synonym: "MOP5" RELATED Gene-based [UniProtKB:Q9Y3Z3]
synonym: "SAMHD1" RELATED Gene-based [UniProtKB:Q9Y3Z3]
synonym: "hSAMHD1" EXACT PRO-short-label [PRO:DNx]
synonym: "DCIP (human)" EXACT [UniProtKB:Q9Y3Z3]
synonym: "MOP-5 (human)" EXACT [UniProtKB:Q9Y3Z3]
synonym: "dNTPase (human)" EXACT [UniProtKB:Q9Y3Z3]
synonym: "monocyte protein 5 (human)" EXACT [UniProtKB:Q9Y3Z3]
synonym: "dendritic cell-derived IFNG-induced protein (human)" EXACT [UniProtKB:Q9Y3Z3]
synonym: "SAM domain and HD domain-containing protein 1 (human)" EXACT []
xref: Reactome:R-HSA-5624198 "PR:Q9Y3Z3 located_in GO:0005654"
xref: UniProtKB:Q9Y3Z3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014443 ! deoxynucleoside triphosphate triphosphohydrolase SAMHD1
relationship: has_gene_template HGNC:15925 ! SAMHD1 (human)

[Term]
id: PR:Q9Y3Z3-4
name: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform h4 (human)
def: "A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y3Z3-4." [PRO:DNx, UniProtKB:Q9Y3Z3]
comment: Category=organism-sequence.
synonym: "hSAMHD1/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform delta14 (human)" EXACT [UniProtKB:Q9Y3Z3]
xref: UniProtKB:Q9Y3Z3-4
is_a: PR:Q9Y3Z3 ! deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens