[Term] id: PR:P05121-1 name: plasminogen activator inhibitor 1 isoform 1 (human) def: "A plasminogen activator inhibitor 1 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hSERPINE1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05121-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038665 ! plasminogen activator inhibitor 1 isoform 1 [Term] id: PR:P22777 name: plasminogen activator inhibitor 1 (mouse) def: "A plasminogen activator inhibitor 1 that is encoded in the genome of mouse." [OMA:P22777, PRO:DNx] comment: Category=organism-gene. synonym: "Mr1" RELATED Gene-based [UniProtKB:P22777] synonym: "Pai1" RELATED Gene-based [UniProtKB:P22777] synonym: "Planh1" RELATED Gene-based [UniProtKB:P22777] synonym: "Serpine1" RELATED Gene-based [UniProtKB:P22777] synonym: "mSERPINE1" EXACT PRO-short-label [PRO:DNx] synonym: "PAI (mouse)" EXACT [UniProtKB:P22777] synonym: "PAI-1 (mouse)" EXACT [UniProtKB:P22777] synonym: "serpin E1 (mouse)" EXACT [UniProtKB:P22777] synonym: "endothelial plasminogen activator inhibitor (mouse)" EXACT [UniProtKB:P22777] xref: UniProtKB:P22777 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000014702 ! plasminogen activator inhibitor 1 relationship: has_gene_template MGI:97608 ! Serpine1 (mouse) [Term] id: PR:000049208 name: plasminogen activator inhibitor 1, signal peptide removed form (human) def: "A plasminogen activator inhibitor 1 (human) that has had the signal peptide removed. UniProtKB:P05121, 24-402." [PRO:DNx, Reactome:R-HSA-114649, Reactome:R-HSA-158922] comment: Category=organism-modification. synonym: "PRO_0000032499" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hSERPINE1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121, 24-402" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-114649 "PR:000049208 located_in GO:0031093" xref: Reactome:R-HSA-61271 "PR:000049208 located_in GO:0005576" xref: Reactome:R-HSA-158797 "PR:000049208 located_in GO:0005576" xref: Reactome:R-HSA-158922 "PR:000049208 located_in GO:0005886" intersection_of: PR:P05121 ! plasminogen activator inhibitor 1 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P20961 name: plasminogen activator inhibitor 1 (rat) def: "A plasminogen activator inhibitor 1 that is encoded in the genome of rat." [OMA:P20961, PANTHER:PTHR11461:SF49, PRO:DNx] comment: Category=organism-gene. synonym: "Pai1" RELATED Gene-based [UniProtKB:P20961] synonym: "Planh1" RELATED Gene-based [UniProtKB:P20961] synonym: "Serpine1" RELATED Gene-based [UniProtKB:P20961] synonym: "PAI (rat)" EXACT [UniProtKB:P20961] synonym: "rSERPINE1" EXACT PRO-short-label [PRO:DNx] synonym: "PAI-1 (rat)" EXACT [UniProtKB:P20961] synonym: "serpin E1 (rat)" EXACT [UniProtKB:P20961] synonym: "endothelial plasminogen activator inhibitor (rat)" EXACT [UniProtKB:P20961] xref: UniProtKB:P20961 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000014702 ! plasminogen activator inhibitor 1 relationship: has_gene_template RGD:3249 ! Serpine1 (rat) [Term] id: PR:000053457 name: plasminogen activator inhibitor 1 O-glycosylated 2 (human) def: "A plasminogen activator inhibitor 1 (human) that has been O-glycosylated at the residue equivalent to Ser-359 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P05121-1, Ser-359, MOD:00002~GNO:G43417UB." [GlyGen:P05121-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Ser-359, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053456 name: plasminogen activator inhibitor 1 O-glycosylated 1 (human) def: "A plasminogen activator inhibitor 1 (human) that has been O-glycosylated at the residue equivalent to Ser-359 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P05121-1, Ser-359, MOD:00002~GNO:G29068FM." [GlyGen:P05121-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Ser-359, MOD:00002~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053455 name: plasminogen activator inhibitor 1 N-glycosylated 4 (human) def: "A plasminogen activator inhibitor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-288 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G88374WZ." [GlyGen:P05121-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/NGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G88374WZ" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G88374WZ ! G88374WZ relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000021433 name: plasminogen activator inhibitor 1, signal peptide removed form def: "A plasminogen activator inhibitor 1 that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "SERPINE1/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000014702 ! plasminogen activator inhibitor 1 intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000053453 name: plasminogen activator inhibitor 1 N-glycosylated 2 (human) def: "A plasminogen activator inhibitor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-288 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G49955PK. Example: UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G49955PK." [GlyGen:P05121-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G49955PK" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G49955PK ! G49955PK relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053452 name: plasminogen activator inhibitor 1 N-glycosylated 1 (human) def: "A plasminogen activator inhibitor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-288 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G07799LX. Example: UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G07799LX." [GlyGen:P05121-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G07799LX" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G07799LX ! G07799LX relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000038665 name: plasminogen activator inhibitor 1 isoform 1 def: "A plasminogen activator inhibitor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05121-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "SERPINE1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000014702 ! plasminogen activator inhibitor 1 [Term] id: PR:P05121-2 name: plasminogen activator inhibitor 1 isoform h2 (human) def: "A plasminogen activator inhibitor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05121-2." [PRO:DNx, UniProtKB:P05121] comment: Category=organism-sequence. synonym: "hSERPINE1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05121-2 is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000014702 name: plasminogen activator inhibitor 1 def: "A serpin that is a translation product of the human SERPINE1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "Mr1" RELATED Gene-based [] synonym: "PAI" EXACT [] synonym: "PAI1" RELATED Gene-based [] synonym: "PAI-1" EXACT [] synonym: "PLANH1" RELATED Gene-based [] synonym: "SERPINE1" EXACT PRO-short-label [PRO:DNx] synonym: "serpin E1" EXACT [] synonym: "endothelial plasminogen activator inhibitor" EXACT [] is_a: PR:000025875 ! serpin [Term] id: PR:P05121 name: plasminogen activator inhibitor 1 (human) def: "A plasminogen activator inhibitor 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P05121] comment: Category=organism-gene. synonym: "PAI1" RELATED Gene-based [UniProtKB:P05121] synonym: "PLANH1" RELATED Gene-based [UniProtKB:P05121] synonym: "SERPINE1" RELATED Gene-based [UniProtKB:P05121] synonym: "hSERPINE1" EXACT PRO-short-label [PRO:DNx] synonym: "PAI (human)" EXACT [UniProtKB:P05121] synonym: "PAI-1 (human)" EXACT [UniProtKB:P05121] synonym: "serpin E1 (human)" EXACT [UniProtKB:P05121] synonym: "endothelial plasminogen activator inhibitor (human)" EXACT [UniProtKB:P05121] xref: UniProtKB:P05121 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014702 ! plasminogen activator inhibitor 1 relationship: has_gene_template HGNC:8583 ! SERPINE1 (human) [Term] id: PR:000053454 name: plasminogen activator inhibitor 1 N-glycosylated 3 (human) def: "A plasminogen activator inhibitor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-288 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G72791KH. Example: UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G72791KH." [GlyGen:P05121-1, PMID:23345538, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/NGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Asn-288, MOD:00160~GNO:G72791KH" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G72791KH ! G72791KH relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P20961-1 name: plasminogen activator inhibitor 1 isoform 1 (rat) def: "A plasminogen activator inhibitor 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rSERPINE1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P20961-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000038665 ! plasminogen activator inhibitor 1 isoform 1 [Term] id: PR:000053459 name: plasminogen activator inhibitor 1 O-glycosylated 4 (human) def: "A plasminogen activator inhibitor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-362 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P05121-1, Thr-362, MOD:00005~GNO:G43417UB." [GlyGen:P05121-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/OGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Thr-362, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000053458 name: plasminogen activator inhibitor 1 O-glycosylated 3 (human) def: "A plasminogen activator inhibitor 1 (human) that has been O-glycosylated at the residue equivalent to Ser-360 of the amino acid sequence represented by UniProtKB:P05121-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P05121-1, Ser-360, MOD:00002~GNO:G43417UB." [GlyGen:P05121-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSERPINE1/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P05121-1, Ser-360, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:P05121 ! plasminogen activator inhibitor 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens