[Term]
id: PR:000014748
name: splicing factor, arginine/serine-rich 1
def: "A protein that is a translation product of the human SRSF1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ASF" RELATED Gene-based []
synonym: "SF2" RELATED Gene-based []
synonym: "ASF-1" EXACT []
synonym: "SFRS1" RELATED Gene-based []
synonym: "SRSF1" EXACT PRO-short-label [PRO:DNx]
synonym: "SF2P33" RELATED Gene-based []
synonym: "ASF/SF2" EXACT []
synonym: "OK/SW-cl.3" RELATED Gene-based []
synonym: "alternative-splicing factor 1" EXACT []
synonym: "pre-mRNA-splicing factor SF2, P33 subunit" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000049350
name: serine/arginine-rich splicing factor 1, initiator methionine removed form (human)
def: "A serine/arginine-rich splicing factor 1 (human) that has had the initiator methionine removed. UniProtKB:Q07955, 2-248." [PRO:DNx, Reactome:R-HSA-72031]
comment: Category=organism-modification.
synonym: "PRO_0000081911" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hSRSF1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q07955, 2-248" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-72031 "PR:000049350 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q07955 ! serine/arginine-rich splicing factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q07955-1
name: serine/arginine-rich splicing factor 1 isoform ASF-1 (human)
def: "A splicing factor, arginine/serine-rich 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSRSF1/iso:ASF-1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07955-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040326 ! splicing factor, arginine/serine-rich 1 isoform 1

[Term]
id: PR:Q07955-3
name: serine/arginine-rich splicing factor 1 isoform ASF-3 (human)
def: "A splicing factor, arginine/serine-rich 1 isoform 3 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSRSF1/iso:ASF-3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07955-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040327 ! splicing factor, arginine/serine-rich 1 isoform 3

[Term]
id: PR:Q07955-2
name: serine/arginine-rich splicing factor 1 isoform hASF-2 (human)
def: "A serine/arginine-rich splicing factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07955-2." [PRO:DNx, UniProtKB:Q07955]
comment: Category=organism-sequence.
synonym: "hSRSF1/iso:hASF-2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q07955-2
is_a: PR:Q07955 ! serine/arginine-rich splicing factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045889
name: serine/arginine-rich splicing factor 1 phosphorylated 1 (human)
def: "A serine/arginine-rich splicing factor 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-119 of the amino acid sequence represented by UniProtKB:Q07955-1. Example: UniProtKB:Q07955-1, Ser-119, MOD:00046." [PMID:22393468, iPTMnet:Q07955]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22393468). Status=unreviewed.
synonym: "hSRSF1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q07955-1, Ser-119, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q07955 ! serine/arginine-rich splicing factor 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q07955
name: serine/arginine-rich splicing factor 1 (human)
def: "A splicing factor, arginine/serine-rich 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q07955]
comment: Category=organism-gene.
synonym: "ASF" RELATED Gene-based [UniProtKB:Q07955]
synonym: "SF2" RELATED Gene-based [UniProtKB:Q07955]
synonym: "SFRS1" RELATED Gene-based [UniProtKB:Q07955]
synonym: "SRSF1" RELATED Gene-based [UniProtKB:Q07955]
synonym: "SF2P33" RELATED Gene-based [UniProtKB:Q07955]
synonym: "hSRSF1" EXACT PRO-short-label [PRO:DNx]
synonym: "OK/SW-cl.3" RELATED Gene-based [UniProtKB:Q07955]
synonym: "ASF-1 (human)" EXACT [UniProtKB:Q07955]
synonym: "alternative-splicing factor 1 (human)" EXACT [UniProtKB:Q07955]
synonym: "splicing factor, arginine/serine-rich 1 (human)" EXACT [UniProtKB:Q07955]
synonym: "pre-mRNA-splicing factor SF2, P33 subunit (human)" EXACT [UniProtKB:Q07955]
xref: UniProtKB:Q07955
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014748 ! splicing factor, arginine/serine-rich 1
relationship: has_gene_template HGNC:10780 ! SRSF1 (human)