[Term] id: PR:000014841 name: sonic hedgehog protein def: "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "SHH" EXACT PRO-short-label [PRO:DNx] synonym: "Hhg1" RELATED Gene-based [] synonym: "HHG-1" EXACT [] synonym: "ShhNC" EXACT [] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000037274 name: sonic hedgehog protein N-product dually lipidated 1 (human) def: "A sonic hedgehog protein N-product in human that has been further modified on the N-terminal Cys residue by palmitoylation and the C-terminal Gly residue by cholesterylation. UniProtKB:Q15465, 24-197, Cys-24, MOD:00069|Gly-197, MOD:00314." [PMID:9593755, PRO:CNA] comment: Category=organism-modification. Enzyme=("HHAT"; PR:Q5VTY9). synonym: "hSHH/Clv:Nter/2*Lipid:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:Q15465, 24-197, Cys-24, MOD:00069|Gly-197, MOD:00314" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:000037273 ! sonic hedgehog protein N-product relationship: has_part MOD:00069 ! N-palmitoyl-L-cysteine relationship: has_part MOD:00314 ! glycine cholesterol ester relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q15465 name: sonic hedgehog protein (human) def: "A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465] comment: Category=organism-gene. synonym: "SHH" RELATED Gene-based [UniProtKB:Q15465] synonym: "hSHH" EXACT PRO-short-label [PRO:DNx] synonym: "HHG-1 (human)" EXACT [UniProtKB:Q15465] synonym: "ShhNC (human)" EXACT [UniProtKB:Q15465] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)" EXACT [UniProtKB:Q15465] xref: UniProtKB:Q15465 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014841 ! sonic hedgehog protein relationship: has_gene_template HGNC:10848 ! SHH (human)