[Term]
id: PR:000014924
name: solute carrier family 12 member 1
def: "A protein that is a translation product of the human SLC12A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BSC1" EXACT []
synonym: "NKCC2" RELATED Gene-based []
synonym: "SLC12A1" EXACT PRO-short-label [PRO:DNx]
synonym: "kidney-specific Na-K-Cl symporter" EXACT []
synonym: "bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2" EXACT []
xref: IUPHARobj:968
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13621
name: solute carrier family 12 member 1 (human)
def: "A solute carrier family 12 member 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13621]
comment: Category=organism-gene.
synonym: "NKCC2" RELATED Gene-based [UniProtKB:Q13621]
synonym: "SLC12A1" RELATED Gene-based [UniProtKB:Q13621]
synonym: "hSLC12A1" EXACT PRO-short-label [PRO:DNx]
synonym: "kidney-specific Na-K-Cl symporter (human)" EXACT [UniProtKB:Q13621]
synonym: "bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 (human)" BROAD [UniProtKB:Q13621]
xref: Reactome:R-HSA-426139 "PR:Q13621 located_in GO:0005886"
xref: UniProtKB:Q13621
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014924 ! solute carrier family 12 member 1
relationship: has_gene_template HGNC:10910 ! SLC12A1 (human)

[Term]
id: PR:P55014-1
name: solute carrier family 12 member 1 isoform A (mouse)
def: "A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-1." [PRO:DNx, UniProtKB:P55014]
comment: Category=organism-sequence.
synonym: "mSlc12a1/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55014-1
is_a: PR:P55014 ! solute carrier family 12 member 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P55014-3
name: solute carrier family 12 member 1 isoform B (mouse)
def: "A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-3." [PRO:DNx, UniProtKB:P55014]
comment: Category=organism-sequence.
synonym: "mSlc12a1/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55014-3
is_a: PR:P55014 ! solute carrier family 12 member 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P55014-2
name: solute carrier family 12 member 1 isoform A4 (mouse)
def: "A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-2." [PRO:DNx, UniProtKB:P55014]
comment: Category=organism-sequence.
synonym: "mSlc12a1/iso:A4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P55014-2
is_a: PR:P55014 ! solute carrier family 12 member 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q13621-2
name: solute carrier family 12 member 1 isoform B (human)
def: "A solute carrier family 12 member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13621-2." [PRO:DNx, UniProtKB:Q13621]
comment: Category=organism-sequence.
synonym: "hSLC12A1/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13621-2
is_a: PR:Q13621 ! solute carrier family 12 member 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P55014-4
name: solute carrier family 12 member 1 isoform F (mouse)
def: "A solute carrier family 12 member 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55014-4." [PRO:DNx, UniProtKB:P55014]
comment: Category=organism-sequence.
synonym: "mSlc12a1/iso:F" EXACT PRO-short-label [PRO:DNx]
synonym: "solute carrier family 12 member 1 isoform C9 (mouse)" EXACT [UniProtKB:P55014]
xref: UniProtKB:P55014-4
is_a: PR:P55014 ! solute carrier family 12 member 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q13621-1
name: solute carrier family 12 member 1 isoform A (human)
def: "A solute carrier family 12 member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13621-1." [PRO:DNx, UniProtKB:Q13621]
comment: Category=organism-sequence.
synonym: "hSLC12A1/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13621-1
is_a: PR:Q13621 ! solute carrier family 12 member 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P55014
name: solute carrier family 12 member 1 (mouse)
def: "A solute carrier family 12 member 1 that is encoded in the genome of mouse." [OMA:P55014, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nkcc2" RELATED Gene-based [UniProtKB:P55014]
synonym: "Slc12a1" RELATED Gene-based [UniProtKB:P55014]
synonym: "mSLC12A1" EXACT PRO-short-label [PRO:DNx]
synonym: "BSC1 (mouse)" EXACT [UniProtKB:P55014]
synonym: "kidney-specific Na-K-Cl symporter (mouse)" EXACT [UniProtKB:P55014]
synonym: "bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 (mouse)" EXACT [UniProtKB:P55014]
xref: UniProtKB:P55014
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014924 ! solute carrier family 12 member 1
relationship: has_gene_template MGI:103150 ! Slc12a1 (mouse)

[Term]
id: PR:P55016
name: solute carrier family 12 member 1 (rat)
def: "A solute carrier family 12 member 1 that is encoded in the genome of rat." [OMA:P55016, PANTHER:PTHR11827:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nkcc2" RELATED Gene-based [UniProtKB:P55016]
synonym: "Slc12a1" RELATED Gene-based [UniProtKB:P55016]
synonym: "rSLC12A1" EXACT PRO-short-label [PRO:DNx]
synonym: "BSC1 (rat)" EXACT [UniProtKB:P55016]
synonym: "kidney-specific Na-K-Cl symporter (rat)" EXACT [UniProtKB:P55016]
synonym: "bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 (rat)" EXACT [UniProtKB:P55016]
xref: UniProtKB:P55016
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000014924 ! solute carrier family 12 member 1
relationship: has_gene_template RGD:3685 ! Slc12a1 (rat)

[Term]
id: PR:Q13621-3
name: solute carrier family 12 member 1 isoform F (human)
def: "A solute carrier family 12 member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13621-3." [PRO:DNx, UniProtKB:Q13621]
comment: Category=organism-sequence.
synonym: "hSLC12A1/iso:F" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13621-3
is_a: PR:Q13621 ! solute carrier family 12 member 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens