[Term]
id: PR:P97690
name: structural maintenance of chromosomes protein 3 (rat)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of rat." [OMA:P97690, PANTHER:PTHR18937:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bam" RELATED Gene-based [UniProtKB:P97690]
synonym: "Bmh" RELATED Gene-based [UniProtKB:P97690]
synonym: "Smc3" RELATED Gene-based [UniProtKB:P97690]
synonym: "Cspg6" RELATED Gene-based [UniProtKB:P97690]
synonym: "rSMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "Smc3l1" RELATED Gene-based [UniProtKB:P97690]
synonym: "SMC-3 (rat)" EXACT [UniProtKB:P97690]
synonym: "bamacan (rat)" EXACT [UniProtKB:P97690]
synonym: "SMC protein 3 (rat)" EXACT [UniProtKB:P97690]
synonym: "chondroitin sulfate proteoglycan 6 (rat)" EXACT [UniProtKB:P97690]
synonym: "chromosome segregation protein SmcD (rat)" EXACT [UniProtKB:P97690]
synonym: "basement membrane-associated chondroitin proteoglycan (rat)" EXACT [UniProtKB:P97690]
xref: UniProtKB:P97690
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template RGD:62006 ! Smc3 (rat)

[Term]
id: PR:P47037
name: structural maintenance of chromosomes protein 3 (yeast)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of yeast." [OMA:P47037, PANTHER:PTHR18937:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "SMC3" RELATED Gene-based [UniProtKB:P47037]
synonym: "J1049" RELATED Gene-based [UniProtKB:P47037]
synonym: "ySMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "YJL074C" RELATED Gene-based [UniProtKB:P47037]
synonym: "DA-box protein SMC3 (yeast)" EXACT [UniProtKB:P47037]
xref: UniProtKB:P47037
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template SGD:S000003610 ! SMC3 (yeast)

[Term]
id: PR:Q56YN8
name: structural maintenance of chromosomes protein 3 (Arabidopsis thaliana)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q56YN8, PRO:DAN]
comment: Category=organism-gene.
synonym: "SMC3" RELATED Gene-based [UniProtKB:Q56YN8]
synonym: "TTN7" RELATED Gene-based [UniProtKB:Q56YN8]
synonym: "At-SMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "T22O13.6" RELATED Gene-based [UniProtKB:Q56YN8]
synonym: "At2g27170" RELATED Gene-based [UniProtKB:Q56YN8]
synonym: "SMC-3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q56YN8]
synonym: "SMC protein 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q56YN8]
synonym: "protein TITAN7 (Arabidopsis thaliana)" EXACT [UniProtKB:Q56YN8]
synonym: "cohesin complex subunit SMC-3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q56YN8]
synonym: "chromosome segregation protein SMC-3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q56YN8]
xref: UniProtKB:Q56YN8
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template Araport:AT2G27170 ! SMC3 (Arabidopsis thaliana)

[Term]
id: PR:Q9UQE7-1
name: structural maintenance of chromosomes protein 3 isoform 1 (human)
def: "A structural maintenance of chromosomes protein 3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSMC3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UQE7-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044057 ! structural maintenance of chromosomes protein 3 isoform 1

[Term]
id: PR:000044057
name: structural maintenance of chromosomes protein 3 isoform 1
def: "A structural maintenance of chromosomes protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UQE7-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "SMC3/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000015272 ! structural maintenance of chromosomes protein 3

[Term]
id: PR:000049293
name: structural maintenance of chromosomes protein 3 acetylated 1 (human)
def: "A structural maintenance of chromosomes protein 3 (human) that has been post-translationally modified to include N6-acetyllysine at positions 105 and 106 of the amino acid sequence represented by UniProtKB:Q9UQE7. UniProtKB:Q9UQE7, Lys-105/Lys-106, MOD:00064." [PRO:DNx, Reactome:R-HSA-2468050, Reactome:R-HSA-2468146, Reactome:R-HSA-2468148, Reactome:R-HSA-2484792]
comment: Category=organism-modification.
synonym: "hSMC3/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UQE7, Lys-105/Lys-106, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2468050 "PR:000049293 located_in GO:0005654"
xref: Reactome:R-HSA-2468146 "PR:000049293 located_in GO:0005694"
xref: Reactome:R-HSA-2468148 "PR:000049293 located_in GO:0000775"
xref: Reactome:R-HSA-2484792 "PR:000049293 located_in GO:0005829"
is_a: PR:Q9UQE7 ! structural maintenance of chromosomes protein 3 (human)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q552D9
name: structural maintenance of chromosomes protein 3 (Dictyostelium discoideum)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q552D9, PANTHER:PTHR18937:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "smc3" RELATED Gene-based [UniProtKB:Q552D9]
synonym: "Dicty-SMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0276101" RELATED Gene-based [UniProtKB:Q552D9]
synonym: "SMC-3 (Dictyostelium discoideum)" EXACT [UniProtKB:Q552D9]
synonym: "SMC protein 3 (Dictyostelium discoideum)" EXACT [UniProtKB:Q552D9]
xref: UniProtKB:Q552D9
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template dictyBase:DDB_G0276101 ! smc3 (Dictyostelium discoideum)

[Term]
id: PR:000037033
name: mitotic cohesin complex subunit Psm3/Smc3 acetylated 1 (Schizosaccharomyces pombe)
def: "A mitotic cohesin complex subunit Psm3/Smc3 (Schizosaccharomyces pombe) that has been acetylated on two Lys residues equivalent to Lys-105 and Lys-106 of the amino acid sequence represented by UniProtKB:O42649. Example: UniProtKB:O42649, Lys-105/Lys-106, MOD:00064." [PMID:21300781, PMID:26687354, PRO:DAN, PomBase:VW]
comment: Category=organism-modification. Requested by=PomBase.
synonym: "Spom-psm3/Ac:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:O42649, Lys-105/Lys-106, MOD:00064" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "cohesin complex Psm3 subunit acetylated 1 (Schizosaccharomyces pombe)" EXACT []
synonym: "structural maintenance of chromosomes protein 3 acetylated 1 (Schizosaccharomyces pombe)" EXACT []
is_a: PR:000037032 ! mitotic cohesin complex subunit Psm3/Smc3 (Schizosaccharomyces pombe)
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine
relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe

[Term]
id: PR:000037032
name: mitotic cohesin complex subunit Psm3/Smc3 (Schizosaccharomyces pombe)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of Schizosaccharomyces pombe." [PRO:DAN]
comment: Category=organism-gene. Requested by=PomBase.
synonym: "Spom-psm3" EXACT PRO-short-label [PRO:DAN]
synonym: "cohesin complex Psm3 subunit (Schizosaccharomyces pombe)" EXACT []
synonym: "structural maintenance of chromosomes protein 3 (Schizosaccharomyces pombe)" EXACT []
intersection_of: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template PomBase:SPAC10F6.09c ! psm3 (Schizosaccharomyces pombe)

[Term]
id: PR:Q9CW03-1
name: structural maintenance of chromosomes protein 3 isoform 1 (mouse)
def: "A structural maintenance of chromosomes protein 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mSMC3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9CW03-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044057 ! structural maintenance of chromosomes protein 3 isoform 1

[Term]
id: PR:B2FDA8-1
name: structural maintenance of chromosomes protein 3 isoform b (worm)
def: "A structural maintenance of chromosomes protein 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B2FDA8-1." [PRO:DNx, UniProtKB:B2FDA8]
comment: Category=organism-sequence.
synonym: "SMC3/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2FDA8-1
is_a: PR:B2FDA8 ! structural maintenance of chromosomes protein 3 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:B2FDA8
name: structural maintenance of chromosomes protein 3 (worm)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of worm." [OMA:B2FDA8, PANTHER:PTHR18937:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "smc-3" RELATED Gene-based [UniProtKB:B2FDA8]
synonym: "Y47D3A.26" RELATED Gene-based [UniProtKB:B2FDA8]
synonym: "SMC3 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2FDA8
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template WormBase:WBGene00004873 ! smc-3 (worm)

[Term]
id: PR:B2FDA8-3
name: structural maintenance of chromosomes protein 3 isoform c (worm)
def: "A structural maintenance of chromosomes protein 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B2FDA8-3." [PRO:DNx, UniProtKB:B2FDA8]
comment: Category=organism-sequence.
synonym: "SMC3/iso:c (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2FDA8-3
is_a: PR:B2FDA8 ! structural maintenance of chromosomes protein 3 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:B2FDA8-2
name: structural maintenance of chromosomes protein 3 isoform a (worm)
def: "A structural maintenance of chromosomes protein 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B2FDA8-2." [PRO:DNx, UniProtKB:B2FDA8]
comment: Category=organism-sequence.
synonym: "SMC3/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2FDA8-2
is_a: PR:B2FDA8 ! structural maintenance of chromosomes protein 3 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:O42649
name: structural maintenance of chromosomes protein 3 (Schizosaccharomyces pombe 972h-)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O42649, PRO:DNx]
comment: Category=organism-gene.
synonym: "psm3" RELATED Gene-based [UniProtKB:O42649]
synonym: "smc3" RELATED Gene-based [UniProtKB:O42649]
synonym: "SPAC10F6.09c" RELATED Gene-based [UniProtKB:O42649]
synonym: "Spom972h-SMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "cohesin complex Psm3 subunit (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O42649]
xref: UniProtKB:O42649
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template PomBase:SPAC10F6.09c ! psm3 (Schizosaccharomyces pombe)

[Term]
id: PR:000015272
name: structural maintenance of chromosomes protein 3
def: "A protein that is a translation product of the human SMC3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BAM" RELATED Gene-based []
synonym: "BMH" RELATED Gene-based []
synonym: "CAP" EXACT []
synonym: "SMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "Smcd" RELATED Gene-based []
synonym: "CSPG6" RELATED Gene-based []
synonym: "Mmip1" RELATED Gene-based []
synonym: "SMC-3" EXACT []
synonym: "SMC3L1" RELATED Gene-based []
synonym: "bamacan" EXACT []
synonym: "SMC protein 3" EXACT []
synonym: "Mad member-interacting protein 1" EXACT []
synonym: "chromosome-associated polypeptide" EXACT []
synonym: "chondroitin sulfate proteoglycan 6" EXACT []
synonym: "chromosome segregation protein SmcD" EXACT []
synonym: "basement membrane-associated chondroitin proteoglycan" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9CW03
name: structural maintenance of chromosomes protein 3 (mouse)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of mouse." [OMA:Q9CW03, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bam" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "Bmh" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "Smc3" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "Smcd" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "Cspg6" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "Mmip1" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "mSMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "Smc3l1" RELATED Gene-based [UniProtKB:Q9CW03]
synonym: "SMC-3 (mouse)" EXACT [UniProtKB:Q9CW03]
synonym: "bamacan (mouse)" EXACT [UniProtKB:Q9CW03]
synonym: "SMC protein 3 (mouse)" EXACT [UniProtKB:Q9CW03]
synonym: "Mad member-interacting protein 1 (mouse)" EXACT [UniProtKB:Q9CW03]
synonym: "chondroitin sulfate proteoglycan 6 (mouse)" EXACT [UniProtKB:Q9CW03]
synonym: "chromosome segregation protein SmcD (mouse)" EXACT [UniProtKB:Q9CW03]
synonym: "basement membrane-associated chondroitin proteoglycan (mouse)" EXACT [UniProtKB:Q9CW03]
xref: UniProtKB:Q9CW03
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template MGI:1339795 ! Smc3 (mouse)

[Term]
id: PR:Q9UQE7
name: structural maintenance of chromosomes protein 3 (human)
def: "A structural maintenance of chromosomes protein 3 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "BAM" RELATED Gene-based [UniProtKB:Q9UQE7]
synonym: "BMH" RELATED Gene-based [UniProtKB:Q9UQE7]
synonym: "SMC3" RELATED Gene-based [UniProtKB:Q9UQE7]
synonym: "hCAP" EXACT [UniProtKB:Q9UQE7]
synonym: "CSPG6" RELATED Gene-based [UniProtKB:Q9UQE7]
synonym: "hSMC3" EXACT PRO-short-label [PRO:DNx]
synonym: "SMC3L1" RELATED Gene-based [UniProtKB:Q9UQE7]
synonym: "SMC-3 (human)" EXACT [UniProtKB:Q9UQE7]
synonym: "bamacan (human)" EXACT [UniProtKB:Q9UQE7]
synonym: "SMC protein 3 (human)" EXACT [UniProtKB:Q9UQE7]
synonym: "chromosome-associated polypeptide (human)" EXACT [UniProtKB:Q9UQE7]
synonym: "chondroitin sulfate proteoglycan 6 (human)" EXACT [UniProtKB:Q9UQE7]
synonym: "basement membrane-associated chondroitin proteoglycan (human)" EXACT [UniProtKB:Q9UQE7]
xref: Reactome:R-HSA-163009 "PR:Q9UQE7 located_in GO:0005654"
xref: Reactome:R-HSA-2545223 "PR:Q9UQE7 located_in GO:0005829"
xref: UniProtKB:Q9UQE7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015272 ! structural maintenance of chromosomes protein 3
relationship: has_gene_template HGNC:2468 ! SMC3 (human)