[Term]
id: PR:P08294
name: extracellular superoxide dismutase [Cu-Zn] (human)
def: "An extracellular superoxide dismutase [Cu-Zn] that is encoded in the genome of human." [PRO:DNx, UniProtKB:P08294]
comment: Category=organism-gene.
synonym: "SOD3" RELATED Gene-based [UniProtKB:P08294]
synonym: "hSOD3" EXACT PRO-short-label [PRO:DNx]
synonym: "EC-SOD (human)" EXACT [UniProtKB:P08294]
xref: UniProtKB:P08294
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015401 ! extracellular superoxide dismutase [Cu-Zn]
relationship: has_gene_template HGNC:11181 ! SOD3 (human)

[Term]
id: PR:000049320
name: extracellular superoxide dismutase [Cu-Zn], signal peptide removed form (human)
def: "An extracellular superoxide dismutase [Cu-Zn] (human) that has had the signal peptide removed. UniProtKB:P08294, 19-240." [PRO:DNx, Reactome:R-HSA-3299690, Reactome:R-HSA-3697878]
comment: Category=organism-modification.
synonym: "hSOD3/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000032855" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P08294, 19-240" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3299690 "PR:000049320 located_in GO:0005576"
xref: Reactome:R-HSA-3697878 "PR:000049320 located_in GO:0005796"
intersection_of: PR:P08294 ! extracellular superoxide dismutase [Cu-Zn] (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054445
name: extracellular superoxide dismutase [Cu-Zn] O-glycosylated 1 (human)
def: "An extracellular superoxide dismutase [Cu-Zn] (human) that has been O-glycosylated at the residue equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:P08294-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08294-1, Ser-29, MOD:00002~GNO:G43417UB." [GlyGen:P08294-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSOD3/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08294-1, Ser-29, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P08294 ! extracellular superoxide dismutase [Cu-Zn] (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000015401
name: extracellular superoxide dismutase [Cu-Zn]
def: "A SODC domain protein that is a translation product of the human SOD3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SOD3" EXACT PRO-short-label [PRO:DNx]
synonym: "EC-SOD" EXACT []
is_a: PR:000039980 ! SODC domain protein