[Term]
id: PR:Q9WU03
name: Kunitz-type protease inhibitor 2 (mouse)
def: "A Kunitz-type protease inhibitor 2 that is encoded in the genome of mouse." [OMA:Q9WU03, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hai2" RELATED Gene-based [UniProtKB:Q9WU03]
synonym: "Spint2" RELATED Gene-based [UniProtKB:Q9WU03]
synonym: "mSPINT2" EXACT PRO-short-label [PRO:DNx]
synonym: "HAI-2 (mouse)" EXACT [UniProtKB:Q9WU03]
synonym: "hepatocyte growth factor activator inhibitor type 2 (mouse)" EXACT [UniProtKB:Q9WU03]
xref: UniProtKB:Q9WU03
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000015543 ! Kunitz-type protease inhibitor 2
relationship: has_gene_template MGI:1338031 ! Spint2 (mouse)

[Term]
id: PR:O43291-2
name: Kunitz-type protease inhibitor 2 isoform 2 (human)
def: "A Kunitz-type protease inhibitor 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSPINT2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43291-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038122 ! Kunitz-type protease inhibitor 2 isoform 2

[Term]
id: PR:000050740
name: Kunitz-type protease inhibitor 2 O-glycosylated 1 (human)
def: "A Kunitz-type protease inhibitor 2 (human) that has been O-glycosylated at the residue equivalent to Thr-134 of the amino acid sequence represented by UniProtKB:O43291-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O43291-1, Thr-134, MOD:00005~GNO:G43417UB." [GlyGen:O43291-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPINT2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43291-1, Thr-134, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O43291 ! Kunitz-type protease inhibitor 2 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9WU03-1
name: Kunitz-type protease inhibitor 2 isoform 1 (mouse)
def: "A Kunitz-type protease inhibitor 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mSPINT2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9WU03-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038121 ! Kunitz-type protease inhibitor 2 isoform 1

[Term]
id: PR:Q9WU03-3
name: Kunitz-type protease inhibitor 2 isoform m3 (mouse)
def: "A Kunitz-type protease inhibitor 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WU03-3." [PRO:DNx, UniProtKB:Q9WU03]
comment: Category=organism-sequence.
synonym: "mSPINT2/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9WU03-3
is_a: PR:Q9WU03 ! Kunitz-type protease inhibitor 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9WU03-2
name: Kunitz-type protease inhibitor 2 isoform 2 (mouse)
def: "A Kunitz-type protease inhibitor 2 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mSPINT2/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9WU03-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038122 ! Kunitz-type protease inhibitor 2 isoform 2

[Term]
id: PR:000038121
name: Kunitz-type protease inhibitor 2 isoform 1
def: "A Kunitz-type protease inhibitor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43291-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "SPINT2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000015543 ! Kunitz-type protease inhibitor 2

[Term]
id: PR:000038122
name: Kunitz-type protease inhibitor 2 isoform 2
def: "A Kunitz-type protease inhibitor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43291-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "SPINT2/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000015543 ! Kunitz-type protease inhibitor 2

[Term]
id: PR:O43291-1
name: Kunitz-type protease inhibitor 2 isoform 1 (human)
def: "A Kunitz-type protease inhibitor 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSPINT2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43291-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038121 ! Kunitz-type protease inhibitor 2 isoform 1

[Term]
id: PR:000015543
name: Kunitz-type protease inhibitor 2
def: "A protein that is a translation product of the human SPINT2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "KOP" RELATED Gene-based []
synonym: "HAI2" RELATED Gene-based []
synonym: "HAI-2" EXACT []
synonym: "SPINT2" EXACT PRO-short-label [PRO:DNx]
synonym: "placental bikunin" EXACT []
synonym: "hepatocyte growth factor activator inhibitor type 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000049327
name: Kunitz-type protease inhibitor 2, signal peptide removed form (human)
def: "A Kunitz-type protease inhibitor 2 (human) that has had the signal peptide removed. UniProtKB:O43291, 28-252." [PRO:DNx, Reactome:R-HSA-6800233]
comment: Category=organism-modification.
synonym: "PRO_0000016885" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hSPINT2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43291, 28-252" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6800233 "PR:000049327 located_in GO:0005576"
intersection_of: PR:O43291 ! Kunitz-type protease inhibitor 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000021558
name: Kunitz-type protease inhibitor 2, signal peptide removed form
def: "A Kunitz-type protease inhibitor 2 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "SPINT2/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000015543 ! Kunitz-type protease inhibitor 2
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:O43291
name: Kunitz-type protease inhibitor 2 (human)
def: "A Kunitz-type protease inhibitor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43291]
comment: Category=organism-gene.
synonym: "KOP" RELATED Gene-based [UniProtKB:O43291]
synonym: "HAI2" RELATED Gene-based [UniProtKB:O43291]
synonym: "SPINT2" RELATED Gene-based [UniProtKB:O43291]
synonym: "hSPINT2" EXACT PRO-short-label [PRO:DNx]
synonym: "HAI-2 (human)" EXACT [UniProtKB:O43291]
synonym: "placental bikunin (human)" EXACT [UniProtKB:O43291]
synonym: "hepatocyte growth factor activator inhibitor type 2 (human)" EXACT [UniProtKB:O43291]
xref: UniProtKB:O43291
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015543 ! Kunitz-type protease inhibitor 2
relationship: has_gene_template HGNC:11247 ! SPINT2 (human)