[Term]
id: PR:000015597
name: serine palmitoyltransferase 2
def: "A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "LCB2" RELATED Gene-based []
synonym: "LCB 2" EXACT []
synonym: "LCB2a" EXACT []
synonym: "SPT 2" EXACT []
synonym: "SPTLC2" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0526" RELATED Gene-based []
synonym: "serine-palmitoyl-CoA transferase 2" EXACT []
synonym: "long chain base biosynthesis protein 2" EXACT []
synonym: "long chain base biosynthesis protein 2a" EXACT []
xref: IUPHARobj:2510
is_a: PR:000026126 ! eukaryotic serine palmitoyltransferase

[Term]
id: PR:O15270
name: serine palmitoyltransferase 2 (human)
def: "A serine palmitoyltransferase 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-gene.
synonym: "LCB2" RELATED Gene-based [UniProtKB:O15270]
synonym: "SPTLC2" RELATED Gene-based [UniProtKB:O15270]
synonym: "hSPTLC2" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0526" RELATED Gene-based [UniProtKB:O15270]
synonym: "LCB 2 (human)" EXACT [UniProtKB:O15270]
synonym: "LCB2a (human)" EXACT [UniProtKB:O15270]
synonym: "SPT 2 (human)" EXACT [UniProtKB:O15270]
synonym: "serine-palmitoyl-CoA transferase 2 (human)" EXACT [UniProtKB:O15270]
synonym: "long chain base biosynthesis protein 2 (human)" EXACT [UniProtKB:O15270]
synonym: "long chain base biosynthesis protein 2a (human)" EXACT [UniProtKB:O15270]
xref: UniProtKB:O15270
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015597 ! serine palmitoyltransferase 2
relationship: has_gene_template HGNC:11278 ! SPTLC2 (human)

[Term]
id: PR:000049342
name: serine palmitoyltransferase 2 pyridoxal phosphate lysine 1 (human)
def: "A serine palmitoyltransferase 2 (human) that has been post-translationally modified to include pyridoxal phosphate lysine at position 379 of the amino acid sequence represented by UniProtKB:O15270. UniProtKB:O15270, Lys-379, MOD:00128." [PRO:DNx, Reactome:R-HSA-428146]
comment: Category=organism-modification.
synonym: "hSPTLC2/Pyrdox:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15270, Lys-379, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-428146 "PR:000049342 located_in GO:0005789"
is_a: PR:O15270 ! serine palmitoyltransferase 2 (human)
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P97363-1
name: serine palmitoyltransferase 2 isoform 1 (mouse)
def: "A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "mSPTLC2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97363-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000022020 ! serine palmitoyltransferase 2 isoform 1

[Term]
id: PR:Q3B7D2
name: serine palmitoyltransferase 2 (rat)
def: "A serine palmitoyltransferase 2 that is encoded in the genome of rat." [PRO:CNA]
comment: Category=organism-gene.
synonym: "Lcb2" RELATED Gene-based [UniProtKB:Q3B7D2]
synonym: "Pomt2" RELATED Gene-based [UniProtKB:Q3B7D2]
synonym: "Sptlc2" RELATED Gene-based [UniProtKB:Q3B7D2]
synonym: "rSPTLC2" EXACT PRO-short-label [PRO:DNx]
synonym: "LCB 2 (rat)" EXACT [UniProtKB:Q3B7D2]
synonym: "SPT 2 (rat)" EXACT [UniProtKB:Q3B7D2]
synonym: "serine-palmitoyl-CoA transferase 2 (rat)" EXACT [UniProtKB:Q3B7D2]
synonym: "long chain base biosynthesis protein 2 (rat)" EXACT [UniProtKB:Q3B7D2]
xref: UniProtKB:Q3B7D2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000015597 ! serine palmitoyltransferase 2
relationship: has_gene_template RGD:1305447 ! Sptlc2 (rat)

[Term]
id: PR:000022020
name: serine palmitoyltransferase 2 isoform 1
def: "A serine palmitoyltransferase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97363-1 or a 1:1 ortholog thereof." [PMID:8921873, PRO:HJD]
comment: Category=sequence.
synonym: "SPTLC2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000015597 ! serine palmitoyltransferase 2

[Term]
id: PR:O15270-1
name: serine palmitoyltransferase 2 isoform 1 (human)
def: "A serine palmitoyltransferase 2 isoform 1 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hSPTLC2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15270-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000022020 ! serine palmitoyltransferase 2 isoform 1

[Term]
id: PR:P97363
name: serine palmitoyltransferase 2 (mouse)
def: "A serine palmitoyltransferase 2 that is encoded in the genome of mouse." [OMA:P97363, PRO:HJD]
comment: Category=organism-gene.
synonym: "Lcb2" RELATED Gene-based [UniProtKB:P97363]
synonym: "Sptlc2" RELATED Gene-based [UniProtKB:P97363]
synonym: "mSPTLC2" EXACT PRO-short-label [PRO:DNx]
synonym: "LCB 2 (mouse)" EXACT [UniProtKB:P97363]
synonym: "LCB2a (mouse)" EXACT [UniProtKB:P97363]
synonym: "SPT 2 (mouse)" EXACT [UniProtKB:P97363]
synonym: "serine-palmitoyl-CoA transferase 2 (mouse)" EXACT [UniProtKB:P97363]
synonym: "long chain base biosynthesis protein 2 (mouse)" EXACT [UniProtKB:P97363]
synonym: "long chain base biosynthesis protein 2a (mouse)" EXACT [UniProtKB:P97363]
xref: UniProtKB:P97363
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000015597 ! serine palmitoyltransferase 2
relationship: has_gene_template MGI:108074 ! Sptlc2 (mouse)