[Term]
id: PR:000015757
name: serine/threonine-protein kinase 4
def: "A protein that is a translation product of the human STK4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "KRS2" RELATED Gene-based []
synonym: "MST1" RELATED Gene-based []
synonym: "STK4" EXACT PRO-short-label [PRO:DNx]
synonym: "MST-1" EXACT []
synonym: "STE20-like kinase MST1" EXACT []
synonym: "mammalian STE20-like protein kinase 1" EXACT []
synonym: "serine/threonine-protein kinase Krs-2" EXACT []
xref: IUPHARobj:2225
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13043-2
name: serine/threonine-protein kinase 4 isoform h2 (human)
def: "A serine/threonine-protein kinase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13043-2." [PRO:DNx, UniProtKB:Q13043]
comment: Category=organism-sequence.
synonym: "hSTK4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13043-2
is_a: PR:Q13043 ! serine/threonine-protein kinase 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NB31-1
name: serine/threonine-protein kinase cst-1 isoform b (worm)
def: "A serine/threonine-protein kinase cst-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NB31-1." [PRO:DNx, UniProtKB:Q9NB31]
comment: Category=organism-sequence.
synonym: "STK4/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NB31-1
is_a: PR:Q9NB31 ! serine/threonine-protein kinase cst-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:000035909
name: serine/threonine-protein kinase 4 37kDa subunit (human)
def: "A serine/threonine-protein kinase 4 37kDa subunit in human. Example: UniProtKB:Q13043-1, 1-326, Thr-183, MOD:00047." [PMID:11278283, PMID:9545236, Reactome:R-HSA-2028682]
comment: Category=organism-modification.
synonym: "hSTK4/Clv:37kDa" EXACT PRO-short-label [PRO:DAN]
synonym: "p-STK4/N (human)" EXACT [Reactome:R-HSA-2028682]
synonym: "UniProtKB:Q13043-1, 1-326, Thr-183, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2028682 "PR:000035909 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035908 ! serine/threonine-protein kinase 4 37kDa subunit
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:Q13043
name: serine/threonine-protein kinase 4 (human)
def: "A serine/threonine-protein kinase 4 that is encoded in the genome of human." [PMID:20171103, PRO:KER]
comment: Category=organism-gene.
synonym: "KRS2" RELATED Gene-based [UniProtKB:Q13043]
synonym: "MST1" RELATED Gene-based [UniProtKB:Q13043]
synonym: "STK4" RELATED Gene-based [UniProtKB:Q13043]
synonym: "hSTK4" EXACT PRO-short-label [PRO:DNx]
synonym: "MST-1 (human)" EXACT [UniProtKB:Q13043]
synonym: "STE20-like kinase MST1 (human)" EXACT [UniProtKB:Q13043]
synonym: "mammalian STE20-like protein kinase 1 (human)" EXACT [UniProtKB:Q13043]
synonym: "serine/threonine-protein kinase Krs-2 (human)" EXACT [UniProtKB:Q13043]
xref: Reactome:R-HSA-201627 "PR:Q13043 located_in GO:0005829"
xref: DTO:03100508
xref: UniProtKB:Q13043
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015757 ! serine/threonine-protein kinase 4
relationship: has_gene_template HGNC:11408 ! STK4 (human)

[Term]
id: PR:000040388
name: serine/threonine-protein kinase 4 isoform 1
def: "A serine/threonine-protein kinase 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13043-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "STK4/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000015757 ! serine/threonine-protein kinase 4

[Term]
id: PR:Q9NB31-2
name: serine/threonine-protein kinase cst-1 isoform a (worm)
def: "A serine/threonine-protein kinase cst-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NB31-2." [PRO:DNx, UniProtKB:Q9NB31]
comment: Category=organism-sequence.
synonym: "STK4/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NB31-2
is_a: PR:Q9NB31 ! serine/threonine-protein kinase cst-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q13043-1
name: serine/threonine-protein kinase 4 isoform 1 (human)
def: "A serine/threonine-protein kinase 4 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSTK4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13043-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040388 ! serine/threonine-protein kinase 4 isoform 1

[Term]
id: PR:Q9C562
name: CBL-interacting serine/threonine-protein kinase 10 (Arabidopsis thaliana)
def: "A serine/threonine-protein kinase 4 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9C562, PRO:DNx]
comment: Category=organism-gene.
synonym: "PKS2" RELATED Gene-based [UniProtKB:Q9C562]
synonym: "SIP1" RELATED Gene-based [UniProtKB:Q9C562]
synonym: "CIPK10" RELATED Gene-based [UniProtKB:Q9C562]
synonym: "At-STK4" EXACT PRO-short-label [PRO:DNx]
synonym: "MCK7.25" RELATED Gene-based [UniProtKB:Q9C562]
synonym: "SnRK3.8" RELATED Gene-based [UniProtKB:Q9C562]
synonym: "At5g58380" RELATED Gene-based [UniProtKB:Q9C562]
synonym: "SNF1-related kinase 3.8 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9C562]
synonym: "SOS3-interacting protein 1 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9C562]
synonym: "SOS2-like protein kinase PKS2 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9C562]
xref: UniProtKB:Q9C562
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000015757 ! serine/threonine-protein kinase 4
relationship: has_gene_template Araport:AT5G58380 ! CIPK10 (Arabidopsis thaliana)

[Term]
id: PR:Q9JI11-1
name: serine/threonine-protein kinase 4 isoform 1 (mouse)
def: "A serine/threonine-protein kinase 4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mSTK4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JI11-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040388 ! serine/threonine-protein kinase 4 isoform 1

[Term]
id: PR:000049369
name: serine/threonine-protein kinase 4 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase 4 (human) that has been phosphorylated on the residue at the position equivalent to Thr-183 of the amino acid sequence represented by UniProtKB:Q13043. UniProtKB:Q13043, Thr-183, MOD:00047." [PRO:DNx, Reactome:R-HSA-2028258]
comment: Category=organism-modification.
synonym: "hSTK4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13043, Thr-183, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2028258 "PR:000049369 located_in GO:0005829"
is_a: PR:Q13043 ! serine/threonine-protein kinase 4 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NB31
name: serine/threonine-protein kinase cst-1 (worm)
def: "A serine/threonine-protein kinase 4 that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "cst-1" RELATED Gene-based [UniProtKB:Q9NB31]
synonym: "F14H12.4" RELATED Gene-based [UniProtKB:Q9NB31]
synonym: "STK4 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "cMST (worm)" EXACT [UniProtKB:Q9NB31]
synonym: "STE20-like kinase 1 (worm)" EXACT [UniProtKB:Q9NB31]
synonym: "STE20-like kinase MST (worm)" EXACT [UniProtKB:Q9NB31]
xref: UniProtKB:Q9NB31
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000015757 ! serine/threonine-protein kinase 4
relationship: has_gene_template WormBase:WBGene00017472 ! cst-1 (worm)

[Term]
id: PR:Q9JI11
name: serine/threonine-protein kinase 4 (mouse)
def: "A serine/threonine-protein kinase 4 that is encoded in the genome of mouse." [OMA:Q9JI11, PRO:DNx]
comment: Category=organism-gene.
synonym: "Mst1" RELATED Gene-based [UniProtKB:Q9JI11]
synonym: "Stk4" RELATED Gene-based [UniProtKB:Q9JI11]
synonym: "mSTK4" EXACT PRO-short-label [PRO:DNx]
synonym: "MST-1 (mouse)" EXACT [UniProtKB:Q9JI11]
synonym: "STE20-like kinase MST1 (mouse)" EXACT [UniProtKB:Q9JI11]
synonym: "mammalian STE20-like protein kinase 1 (mouse)" EXACT [UniProtKB:Q9JI11]
xref: UniProtKB:Q9JI11
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000015757 ! serine/threonine-protein kinase 4
relationship: has_gene_template MGI:1929004 ! Stk4 (mouse)

[Term]
id: PR:000035908
name: serine/threonine-protein kinase 4 37kDa subunit
def: "A serine/threonine-protein kinase 4 that has been processed by proteolytic cleavage and phosphorylated at a residue equivalent to Thr-183 of the amino acid sequence represented by UniProtKB:Q13043. Example: UniProtKB:Q13043, 1-326, Thr-183, MOD:00047." [PMID:11278283, PMID:9545236, PRO:DAN, Reactome:R-HSA-2028682]
comment: Category=modification.
synonym: "STK4/Clv:37kDa" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000015757 ! serine/threonine-protein kinase 4
relationship: output_of GO:0016485 ! protein processing
relationship: has_part MOD:00047 ! O-phospho-L-threonine