[Term]
id: PR:O14746
name: telomerase reverse transcriptase (human)
def: "A telomerase reverse transcriptase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14746]
comment: Category=organism-gene.
synonym: "TRT" RELATED Gene-based [UniProtKB:O14746]
synonym: "EST2" RELATED Gene-based [UniProtKB:O14746]
synonym: "TCS1" RELATED Gene-based [UniProtKB:O14746]
synonym: "TERT" RELATED Gene-based [UniProtKB:O14746]
synonym: "hTERT" EXACT PRO-short-label [PRO:DNx]
synonym: "TP2 (human)" BROAD [UniProtKB:O14746]
synonym: "HEST2 (human)" EXACT [UniProtKB:O14746]
synonym: "telomerase catalytic subunit (human)" EXACT [UniProtKB:O14746]
synonym: "telomerase-associated protein 2 (human)" EXACT [UniProtKB:O14746]
xref: Reactome:R-HSA-163076 "PR:O14746 located_in GO:0005654"
xref: UniProtKB:O14746
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016238 ! telomerase reverse transcriptase
relationship: has_gene_template HGNC:11730 ! TERT (human)

[Term]
id: PR:000045567
name: telomerase reverse transcriptase phosphorylated 1 (human)
def: "A telomerase reverse transcriptase (human) that has been phosphorylated on the residue at the position equivalent to Tyr-707 of the amino acid sequence represented by UniProtKB:O14746-1. Example: UniProtKB:O14746-1, Tyr-707, MOD:00048." [PMID:12808100, PMID:20211239, iPTMnet:O14746]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12808100, PMID:20211239). Status=unreviewed.
synonym: "hTERT/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14746-1, Tyr-707, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O14746 ! telomerase reverse transcriptase (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016238
name: telomerase reverse transcriptase
def: "A protein that is a translation product of the human TERT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TP2" RELATED []
synonym: "TRT" RELATED Gene-based []
synonym: "EST2" RELATED Gene-based []
synonym: "TCS1" RELATED Gene-based []
synonym: "TERT" EXACT PRO-short-label [PRO:DNx]
synonym: "HEST2" EXACT []
synonym: "telomerase catalytic subunit" EXACT []
synonym: "telomerase-associated protein 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9SPU7
name: telomerase reverse transcriptase (Arabidopsis thaliana)
def: "A telomerase reverse transcriptase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9SPU7, PANTHER:PTHR12066:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "TERT" RELATED Gene-based [UniProtKB:Q9SPU7]
synonym: "AtTERT" EXACT [UniProtKB:Q9SPU7]
synonym: "At-TERT" EXACT PRO-short-label [PRO:DNx]
synonym: "At5g16850" RELATED Gene-based [UniProtKB:Q9SPU7]
synonym: "F5E19.190" RELATED Gene-based [UniProtKB:Q9SPU7]
xref: UniProtKB:Q9SPU7
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000016238 ! telomerase reverse transcriptase
relationship: has_gene_template Araport:AT5G16850 ! TERT (Arabidopsis thaliana)

[Term]
id: PR:Q673L6-2
name: telomerase reverse transcriptase isoform r2 (rat)
def: "A telomerase reverse transcriptase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q673L6-2." [PRO:DNx, UniProtKB:Q673L6]
comment: Category=organism-sequence.
synonym: "rTERT/iso:r2" EXACT PRO-short-label [PRO:DNx]
synonym: "telomerase reverse transcriptase isoform a (rat)" EXACT [UniProtKB:Q673L6]
xref: UniProtKB:Q673L6-2
is_a: PR:Q673L6 ! telomerase reverse transcriptase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q54B44
name: uncharacterized protein, tert translation product (Dictyostelium discoideum)
def: "A telomerase reverse transcriptase that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR12066:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-TERT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54B44
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000016238 ! telomerase reverse transcriptase
relationship: has_gene_template dictyBase:DDB_G0293918 ! tert (Dictyostelium discoideum)

[Term]
id: PR:O70372
name: telomerase reverse transcriptase (mouse)
def: "A telomerase reverse transcriptase that is encoded in the genome of mouse." [OMA:O70372, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tert" RELATED Gene-based [UniProtKB:O70372]
synonym: "mTERT" EXACT PRO-short-label [PRO:DNx]
synonym: "telomerase catalytic subunit (mouse)" EXACT [UniProtKB:O70372]
xref: UniProtKB:O70372
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016238 ! telomerase reverse transcriptase
relationship: has_gene_template MGI:1202709 ! Tert (mouse)

[Term]
id: PR:Q673L6
name: telomerase reverse transcriptase (rat)
def: "A telomerase reverse transcriptase that is encoded in the genome of rat." [OMA:Q673L6, PANTHER:PTHR12066:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tert" RELATED Gene-based [UniProtKB:Q673L6]
synonym: "rTERT" EXACT PRO-short-label [PRO:DNx]
synonym: "telomerase catalytic subunit (rat)" EXACT [UniProtKB:Q673L6]
xref: UniProtKB:Q673L6
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016238 ! telomerase reverse transcriptase
relationship: has_gene_template RGD:70494 ! Tert (rat)

[Term]
id: PR:Q673L6-3
name: telomerase reverse transcriptase isoform r3 (rat)
def: "A telomerase reverse transcriptase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q673L6-3." [PRO:DNx, UniProtKB:Q673L6]
comment: Category=organism-sequence.
synonym: "rTERT/iso:r3" EXACT PRO-short-label [PRO:DNx]
synonym: "telomerase reverse transcriptase isoform b (rat)" EXACT [UniProtKB:Q673L6]
synonym: "telomerase reverse transcriptase isoform c (rat)" EXACT [UniProtKB:Q673L6]
xref: UniProtKB:Q673L6-3
is_a: PR:Q673L6 ! telomerase reverse transcriptase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O13339
name: telomerase reverse transcriptase (Schizosaccharomyces pombe 972h-)
def: "A telomerase reverse transcriptase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR12066:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "trt1" RELATED Gene-based [UniProtKB:O13339]
synonym: "SPBC29A3.14c" RELATED Gene-based [UniProtKB:O13339]
synonym: "Spom972h-TERT" EXACT PRO-short-label [PRO:DNx]
synonym: "telomerase catalytic subunit (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O13339]
xref: UniProtKB:O13339
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000016238 ! telomerase reverse transcriptase
relationship: has_gene_template PomBase:SPBC29A3.14c ! trt1 (Schizosaccharomyces pombe)

[Term]
id: PR:O14746-1
name: telomerase reverse transcriptase isoform 1 (human)
def: "A telomerase reverse transcriptase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14746-1." [PRO:DNx, UniProtKB:O14746]
comment: Category=organism-sequence.
synonym: "hTERT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14746-1
is_a: PR:O14746 ! telomerase reverse transcriptase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q673L6-1
name: telomerase reverse transcriptase isoform r1 (rat)
def: "A telomerase reverse transcriptase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q673L6-1." [PRO:DNx, UniProtKB:Q673L6]
comment: Category=organism-sequence.
synonym: "rTERT/iso:r1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q673L6-1
is_a: PR:Q673L6 ! telomerase reverse transcriptase (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O14746-3
name: telomerase reverse transcriptase isoform h3 (human)
def: "A telomerase reverse transcriptase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14746-3." [PRO:DNx, UniProtKB:O14746]
comment: Category=organism-sequence.
synonym: "hTERT/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14746-3
is_a: PR:O14746 ! telomerase reverse transcriptase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14746-2
name: telomerase reverse transcriptase isoform h2 (human)
def: "A telomerase reverse transcriptase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14746-2." [PRO:DNx, UniProtKB:O14746]
comment: Category=organism-sequence.
synonym: "hTERT/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14746-2
is_a: PR:O14746 ! telomerase reverse transcriptase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O13339-2
name: telomerase reverse transcriptase isoform 2 (Schizosaccharomyces pombe 972h-)
def: "A telomerase reverse transcriptase (Schizosaccharomyces pombe 972h-) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O13339-2." [PRO:DNx, UniProtKB:O13339]
comment: Category=organism-sequence.
synonym: "Spom972h-TERT/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O13339-2
is_a: PR:O13339 ! telomerase reverse transcriptase (Schizosaccharomyces pombe 972h-)
relationship: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-

[Term]
id: PR:O14746-4
name: telomerase reverse transcriptase isoform h4 (human)
def: "A telomerase reverse transcriptase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14746-4." [PRO:DNx, UniProtKB:O14746]
comment: Category=organism-sequence.
synonym: "hTERT/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14746-4
is_a: PR:O14746 ! telomerase reverse transcriptase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O13339-1
name: telomerase reverse transcriptase isoform 1 (Schizosaccharomyces pombe 972h-)
def: "A telomerase reverse transcriptase (Schizosaccharomyces pombe 972h-) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O13339-1." [PRO:DNx, UniProtKB:O13339]
comment: Category=organism-sequence.
synonym: "Spom972h-TERT/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O13339-1
is_a: PR:O13339 ! telomerase reverse transcriptase (Schizosaccharomyces pombe 972h-)
relationship: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-