[Term]
id: PR:000046007
name: DNA topoisomerase 2-binding protein 1 phosphorylated 1 (human)
def: "A DNA topoisomerase 2-binding protein 1 (human) that has been phosphorylated at Ser-1159. UniProtKB:Q92547, Ser-1159, MOD:00046." [PMID:19477925, PMID:24081328, iPTMnet:Q92547]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19477925, PMID:24081328). Status=unreviewed.
synonym: "hTOPBP1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q92547, Ser-1159, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q92547 ! DNA topoisomerase 2-binding protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016548
name: DNA topoisomerase 2-binding protein 1
def: "A protein that is a translation product of the human TOPBP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TOPBP1" EXACT PRO-short-label [PRO:DNx]
synonym: "TopBP1" EXACT []
synonym: "KIAA0259" RELATED Gene-based []
synonym: "DNA topoisomerase II-binding protein 1" EXACT []
synonym: "DNA topoisomerase II-beta-binding protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q92547
name: DNA topoisomerase 2-binding protein 1 (human)
def: "A DNA topoisomerase 2-binding protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92547]
comment: Category=organism-gene.
synonym: "TOPBP1" RELATED Gene-based [UniProtKB:Q92547]
synonym: "hTOPBP1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0259" RELATED Gene-based [UniProtKB:Q92547]
synonym: "TopBP1 (human)" EXACT [UniProtKB:Q92547]
synonym: "DNA topoisomerase II-binding protein 1 (human)" EXACT [UniProtKB:Q92547]
synonym: "DNA topoisomerase II-beta-binding protein 1 (human)" EXACT [UniProtKB:Q92547]
xref: Reactome:R-HSA-5684878 "PR:Q92547 located_in GO:0005654"
xref: UniProtKB:Q92547
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016548 ! DNA topoisomerase 2-binding protein 1
relationship: has_gene_template HGNC:17008 ! TOPBP1 (human)