[Term]
id: PR:Q9NSU2
name: three-prime repair exonuclease 1 (human)
def: "A three-prime repair exonuclease 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NSU2]
comment: Category=organism-gene.
synonym: "TREX1" RELATED Gene-based [UniProtKB:Q9NSU2]
synonym: "hTREX1" EXACT PRO-short-label [PRO:DNx]
synonym: "DNase III (human)" EXACT [UniProtKB:Q9NSU2]
synonym: "deoxyribonuclease III (human)" EXACT [UniProtKB:Q9NSU2]
synonym: "3'-5' exonuclease TREX1 (human)" EXACT [UniProtKB:Q9NSU2]
xref: Reactome:R-HSA-3244651 "PR:Q9NSU2 located_in GO:0005789"
xref: UniProtKB:Q9NSU2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016632 ! three-prime repair exonuclease 1
relationship: has_gene_template HGNC:12269 ! TREX1 (human)

[Term]
id: PR:000016632
name: three-prime repair exonuclease 1
def: "A protein that is a translation product of the human TREX1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TREX1" EXACT PRO-short-label [PRO:DNx]
synonym: "DNase III" EXACT []
synonym: "3'-5' exonuclease TREX1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9NSU2-2
name: three-prime repair exonuclease 1 isoform h2 (human)
def: "A three-prime repair exonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NSU2-2." [PRO:DNx, UniProtKB:Q9NSU2]
comment: Category=organism-sequence.
synonym: "hTREX1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NSU2-2
is_a: PR:Q9NSU2 ! three-prime repair exonuclease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NSU2-3
name: three-prime repair exonuclease 1 isoform h3 (human)
def: "A three-prime repair exonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NSU2-3." [PRO:DNx, UniProtKB:Q9NSU2]
comment: Category=organism-sequence.
synonym: "hTREX1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NSU2-3
is_a: PR:Q9NSU2 ! three-prime repair exonuclease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q91XB0
name: three-prime repair exonuclease 1 (mouse)
def: "A three-prime repair exonuclease 1 that is encoded in the genome of mouse." [OMA:Q91XB0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Trex1" RELATED Gene-based [UniProtKB:Q91XB0]
synonym: "mTREX1" EXACT PRO-short-label [PRO:DNx]
synonym: "3'-5' exonuclease TREX1 (mouse)" EXACT [UniProtKB:Q91XB0]
xref: UniProtKB:Q91XB0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016632 ! three-prime repair exonuclease 1
relationship: has_gene_template MGI:1328317 ! Trex1 (mouse)

[Term]
id: PR:Q9NSU2-1
name: three-prime repair exonuclease 1 isoform h1 (human)
def: "A three-prime repair exonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NSU2-1." [PRO:DNx, UniProtKB:Q9NSU2]
comment: Category=organism-sequence.
synonym: "hTREX1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NSU2-1
is_a: PR:Q9NSU2 ! three-prime repair exonuclease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens