[Term]
id: PR:Q9UKU6
name: thyrotropin-releasing hormone-degrading ectoenzyme (human)
def: "A thyrotropin-releasing hormone-degrading ectoenzyme that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UKU6]
comment: Category=organism-gene.
synonym: "TRHDE" RELATED Gene-based [UniProtKB:Q9UKU6]
synonym: "hTRHDE" EXACT PRO-short-label [PRO:DNx]
synonym: "PAP-II (human)" BROAD [UniProtKB:Q9UKU6]
synonym: "TRH-DE (human)" EXACT [UniProtKB:Q9UKU6]
synonym: "UNQ2507/PRO5995" RELATED Gene-based [UniProtKB:Q9UKU6]
synonym: "thyroliberinase (human)" EXACT [UniProtKB:Q9UKU6]
synonym: "TRH-degrading ectoenzyme (human)" EXACT [UniProtKB:Q9UKU6]
synonym: "pyroglutamyl-peptidase II (human)" EXACT [UniProtKB:Q9UKU6]
synonym: "TRH-specific aminopeptidase (human)" EXACT [UniProtKB:Q9UKU6]
xref: UniProtKB:Q9UKU6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016636 ! thyrotropin-releasing hormone-degrading ectoenzyme
relationship: has_gene_template HGNC:30748 ! TRHDE (human)

[Term]
id: PR:Q8K093
name: thyrotropin-releasing hormone-degrading ectoenzyme (mouse)
def: "A thyrotropin-releasing hormone-degrading ectoenzyme that is encoded in the genome of mouse." [OMA:Q8K093, PRO:DNx]
comment: Category=organism-gene.
synonym: "Trhde" RELATED Gene-based [UniProtKB:Q8K093]
synonym: "mTRHDE" EXACT PRO-short-label [PRO:DNx]
synonym: "PAP-II (mouse)" EXACT [UniProtKB:Q8K093]
synonym: "TRH-DE (mouse)" EXACT [UniProtKB:Q8K093]
synonym: "thyroliberinase (mouse)" EXACT [UniProtKB:Q8K093]
synonym: "TRH-degrading ectoenzyme (mouse)" EXACT [UniProtKB:Q8K093]
synonym: "pyroglutamyl-peptidase II (mouse)" EXACT [UniProtKB:Q8K093]
synonym: "TRH-specific aminopeptidase (mouse)" EXACT [UniProtKB:Q8K093]
xref: UniProtKB:Q8K093
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016636 ! thyrotropin-releasing hormone-degrading ectoenzyme
relationship: has_gene_template MGI:2384311 ! Trhde (mouse)

[Term]
id: PR:Q10836
name: thyrotropin-releasing hormone-degrading ectoenzyme (rat)
def: "A thyrotropin-releasing hormone-degrading ectoenzyme that is encoded in the genome of rat." [PANTHER:PTHR11533:SF40, PRO:DNx]
comment: Category=organism-gene.
synonym: "Trhde" RELATED Gene-based [UniProtKB:Q10836]
synonym: "rTRHDE" EXACT PRO-short-label [PRO:DNx]
synonym: "PAP-II (rat)" EXACT [UniProtKB:Q10836]
synonym: "TRH-DE (rat)" EXACT [UniProtKB:Q10836]
synonym: "thyroliberinase (rat)" EXACT [UniProtKB:Q10836]
synonym: "TRH-degrading ectoenzyme (rat)" EXACT [UniProtKB:Q10836]
synonym: "pyroglutamyl-peptidase II (rat)" EXACT [UniProtKB:Q10836]
synonym: "TRH-specific aminopeptidase (rat)" EXACT [UniProtKB:Q10836]
xref: UniProtKB:Q10836
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016636 ! thyrotropin-releasing hormone-degrading ectoenzyme
relationship: has_gene_template RGD:728895 ! Trhde (rat)

[Term]
id: PR:000016636
name: thyrotropin-releasing hormone-degrading ectoenzyme
def: "A protein that is a translation product of the human TRHDE gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TRHDE" EXACT PRO-short-label [PRO:DNx]
synonym: "PAP-II" RELATED []
synonym: "TRH-DE" EXACT []
synonym: "UNQ2507/PRO5995" RELATED Gene-based []
synonym: "thyroliberinase" EXACT []
synonym: "TRH-degrading ectoenzyme" EXACT []
synonym: "pyroglutamyl-peptidase II" EXACT []
synonym: "TRH-specific aminopeptidase" EXACT []
xref: IUPHARobj:1577
is_a: PR:000000001 ! protein

[Term]
id: PR:000058288
name: thyrotropin-releasing hormone-degrading ectoenzyme O-glycosylated 1 (human)
def: "A thyrotropin-releasing hormone-degrading ectoenzyme (human) that has been O-glycosylated at the residue equivalent to Ser-121 of the amino acid sequence represented by UniProtKB:Q9UKU6-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9UKU6-1, Ser-121, MOD:00002~GNO:G43417UB." [GlyGen:Q9UKU6-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTRHDE/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UKU6-1, Ser-121, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9UKU6 ! thyrotropin-releasing hormone-degrading ectoenzyme (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens