[Term]
id: PR:Q9H3M7
name: thioredoxin-interacting protein (human)
def: "A thioredoxin-interacting protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H3M7]
comment: Category=organism-gene.
synonym: "TXNIP" RELATED Gene-based [UniProtKB:Q9H3M7]
synonym: "VDUP1" RELATED Gene-based [UniProtKB:Q9H3M7]
synonym: "hTXNIP" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin-binding protein 2 (human)" EXACT [UniProtKB:Q9H3M7]
synonym: "vitamin D3 up-regulated protein 1 (human)" EXACT [UniProtKB:Q9H3M7]
xref: Reactome:R-HSA-1250246 "PR:Q9H3M7 located_in GO:0005829"
xref: Reactome:R-HSA-9617747 "PR:Q9H3M7 located_in GO:0005654"
xref: UniProtKB:Q9H3M7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016867 ! thioredoxin-interacting protein
relationship: has_gene_template HGNC:16952 ! TXNIP (human)

[Term]
id: PR:Q8BG60-1
name: thioredoxin-interacting protein isoform m1 (mouse)
def: "A thioredoxin-interacting protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BG60-1." [PRO:DNx, UniProtKB:Q8BG60]
comment: Category=organism-sequence.
synonym: "mTXNIP/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8BG60-1
is_a: PR:Q8BG60 ! thioredoxin-interacting protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8BG60-2
name: thioredoxin-interacting protein isoform m2 (mouse)
def: "A thioredoxin-interacting protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BG60-2." [PRO:DNx, UniProtKB:Q8BG60]
comment: Category=organism-sequence.
synonym: "mTXNIP/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8BG60-2
is_a: PR:Q8BG60 ! thioredoxin-interacting protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000016867
name: thioredoxin-interacting protein
def: "A protein that is a translation product of the human TXNIP gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TXNIP" EXACT PRO-short-label [PRO:DNx]
synonym: "VDUP1" RELATED Gene-based []
synonym: "thioredoxin-binding protein 2" EXACT []
synonym: "vitamin D3 up-regulated protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9H3M7-1
name: thioredoxin-interacting protein isoform h1 (human)
def: "A thioredoxin-interacting protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H3M7-1." [PRO:DNx, UniProtKB:Q9H3M7]
comment: Category=organism-sequence.
synonym: "hTXNIP/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H3M7-1
is_a: PR:Q9H3M7 ! thioredoxin-interacting protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8BG60
name: thioredoxin-interacting protein (mouse)
def: "A thioredoxin-interacting protein that is encoded in the genome of mouse." [OMA:Q8BG60, PRO:DNx]
comment: Category=organism-gene.
synonym: "Txnip" RELATED Gene-based [UniProtKB:Q8BG60]
synonym: "Vdup1" RELATED Gene-based [UniProtKB:Q8BG60]
synonym: "mTXNIP" EXACT PRO-short-label [PRO:DNx]
synonym: "vitamin D3 up-regulated protein 1 (mouse)" EXACT [UniProtKB:Q8BG60]
xref: UniProtKB:Q8BG60
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016867 ! thioredoxin-interacting protein
relationship: has_gene_template MGI:1889549 ! Txnip (mouse)

[Term]
id: PR:Q9H3M7-2
name: thioredoxin-interacting protein isoform h2 (human)
def: "A thioredoxin-interacting protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H3M7-2." [PRO:DNx, UniProtKB:Q9H3M7]
comment: Category=organism-sequence.
synonym: "hTXNIP/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H3M7-2
is_a: PR:Q9H3M7 ! thioredoxin-interacting protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q5M7W1
name: thioredoxin-interacting protein (rat)
def: "A thioredoxin-interacting protein that is encoded in the genome of rat." [OMA:Q5M7W1, PANTHER:PTHR11188:SF14, PRO:DNx]
comment: Category=organism-gene.
synonym: "Txnip" RELATED Gene-based [UniProtKB:Q5M7W1]
synonym: "Vdup1" RELATED Gene-based [UniProtKB:Q5M7W1]
synonym: "rTXNIP" EXACT PRO-short-label [PRO:DNx]
synonym: "vitamin D3 up-regulated protein 1 (rat)" EXACT [UniProtKB:Q5M7W1]
xref: UniProtKB:Q5M7W1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016867 ! thioredoxin-interacting protein
relationship: has_gene_template RGD:620886 ! Txnip (rat)