[Term]
id: PR:Q9R117
name: non-receptor tyrosine-protein kinase TYK2 (mouse)
def: "A non-receptor tyrosine-protein kinase TYK2 that is encoded in the genome of mouse." [OMA:Q9R117, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tyk2" RELATED Gene-based [UniProtKB:Q9R117]
synonym: "mTYK2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9R117
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016874 ! non-receptor tyrosine-protein kinase TYK2
relationship: has_gene_template MGI:1929470 ! Tyk2 (mouse)

[Term]
id: PR:P29597
name: non-receptor tyrosine-protein kinase TYK2 (human)
def: "A non-receptor tyrosine-protein kinase TYK2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P29597]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "TYK2" RELATED Gene-based [UniProtKB:P29597]
synonym: "hTYK2" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-877348 "PR:P29597 located_in GO:0005829"
xref: DTO:03100549
xref: UniProtKB:P29597
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016874 ! non-receptor tyrosine-protein kinase TYK2
relationship: has_gene_template HGNC:12440 ! TYK2 (human)

[Term]
id: PR:000016874
name: non-receptor tyrosine-protein kinase TYK2
def: "A Janus kinase that is a translation product of the human TYK2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TYK2" EXACT PRO-short-label [PRO:DNx]
xref: IUPHARobj:2269
is_a: PR:000025748 ! Janus kinase

[Term]
id: PR:000049570
name: non-receptor tyrosine-protein kinase TYK2 phosphorylated 1 (human)
def: "A non-receptor tyrosine-protein kinase TYK2 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1054 of the amino acid sequence represented by UniProtKB:P29597. UniProtKB:P29597, Tyr-1054, MOD:00048." [PRO:DNx, Reactome:R-HSA-1112598]
comment: Category=organism-modification.
synonym: "hTYK2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P29597, Tyr-1054, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1112598 "PR:000049570 located_in GO:0005829"
is_a: PR:P29597 ! non-receptor tyrosine-protein kinase TYK2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049571
name: non-receptor tyrosine-protein kinase TYK2 phosphorylated 2 (human)
def: "A non-receptor tyrosine-protein kinase TYK2 (human) that has been post-translationally modified to include phosphotyrosine at positions 1054 and 1055 of the amino acid sequence represented by UniProtKB:P29597. UniProtKB:P29597, Tyr-1054/Tyr-1055, MOD:00048." [PRO:DNx, Reactome:R-HSA-909682]
comment: Category=organism-modification.
synonym: "hTYK2/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P29597, Tyr-1054/Tyr-1055, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-909682 "PR:000049571 located_in GO:0005829"
is_a: PR:P29597 ! non-receptor tyrosine-protein kinase TYK2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens