[Term]
id: PR:P51163-1
name: uroporphyrinogen-III synthase isoform 1 (mouse)
def: "A uroporphyrinogen-III synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mUROS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P51163-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038816 ! uroporphyrinogen-III synthase isoform 1

[Term]
id: PR:P87214
name: uroporphyrinogen-III synthase (Schizosaccharomyces pombe 972h-)
def: "A uroporphyrinogen-III synthase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P87214, PANTHER:PTHR12390:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ups" RELATED Gene-based [UniProtKB:P87214]
synonym: "ups1" RELATED Gene-based [UniProtKB:P87214]
synonym: "SPAC31G5.08" RELATED Gene-based [UniProtKB:P87214]
synonym: "Spom972h-UROS" EXACT PRO-short-label [PRO:DNx]
synonym: "UROS (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P87214]
synonym: "UROIIIS (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P87214]
synonym: "uroporphyrinogen-III cosynthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P87214]
synonym: "hydroxymethylbilane hydrolyase [cyclizing] (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P87214]
xref: UniProtKB:P87214
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000017135 ! uroporphyrinogen-III synthase
relationship: has_gene_template PomBase:SPAC31G5.08 ! ups1 (Schizosaccharomyces pombe)

[Term]
id: PR:P10746
name: uroporphyrinogen-III synthase (human)
def: "A uroporphyrinogen-III synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10746]
comment: Category=organism-gene.
synonym: "UROS" RELATED Gene-based [UniProtKB:P10746]
synonym: "hUROS" EXACT PRO-short-label [PRO:DNx]
synonym: "UROIIIS (human)" EXACT [UniProtKB:P10746]
synonym: "uroporphyrinogen-III cosynthase (human)" EXACT [UniProtKB:P10746]
synonym: "hydroxymethylbilane hydrolyase [cyclizing] (human)" EXACT [UniProtKB:P10746]
xref: Reactome:R-HSA-189430 "PR:P10746 located_in GO:0005829"
xref: UniProtKB:P10746
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017135 ! uroporphyrinogen-III synthase
relationship: has_gene_template HGNC:12592 ! UROS (human)

[Term]
id: PR:P06174
name: uroporphyrinogen-III synthase (yeast)
def: "A uroporphyrinogen-III synthase that is encoded in the genome of yeast." [OMA:P06174, PANTHER:PTHR12390:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "HEM4" RELATED Gene-based [UniProtKB:P06174]
synonym: "ORF1" RELATED Gene-based [UniProtKB:P06174]
synonym: "O5463" RELATED Gene-based [UniProtKB:P06174]
synonym: "yUROS" EXACT PRO-short-label [PRO:DNx]
synonym: "YOR278W" RELATED Gene-based [UniProtKB:P06174]
synonym: "UROS (yeast)" EXACT [UniProtKB:P06174]
synonym: "UROIIIS (yeast)" EXACT [UniProtKB:P06174]
synonym: "uroporphyrinogen-III cosynthase (yeast)" EXACT [UniProtKB:P06174]
synonym: "hydroxymethylbilane hydrolyase [cyclizing] (yeast)" EXACT [UniProtKB:P06174]
xref: UniProtKB:P06174
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000017135 ! uroporphyrinogen-III synthase
relationship: has_gene_template SGD:S000005804 ! HEM4 (yeast)

[Term]
id: PR:000017135
name: uroporphyrinogen-III synthase
def: "A protein that is a translation product of the human UROS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "UROS" EXACT PRO-short-label [PRO:DNx]
synonym: "Uros3" RELATED Gene-based []
synonym: "UROIIIS" EXACT []
synonym: "uroporphyrinogen-III cosynthase" BROAD [PRO:DNx]
synonym: "hydroxymethylbilane hydrolyase [cyclizing]" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:P51163
name: uroporphyrinogen-III synthase (mouse)
def: "A uroporphyrinogen-III synthase that is encoded in the genome of mouse." [OMA:P51163, PRO:DNx]
comment: Category=organism-gene.
synonym: "Uros" RELATED Gene-based [UniProtKB:P51163]
synonym: "Uros3" RELATED Gene-based [UniProtKB:P51163]
synonym: "mUROS" EXACT PRO-short-label [PRO:DNx]
synonym: "UROS (mouse)" EXACT [UniProtKB:P51163]
synonym: "UROIIIS (mouse)" EXACT [UniProtKB:P51163]
synonym: "uroporphyrinogen-III cosynthase (mouse)" EXACT [UniProtKB:P51163]
synonym: "hydroxymethylbilane hydrolyase [cyclizing] (mouse)" EXACT [UniProtKB:P51163]
xref: UniProtKB:P51163
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000017135 ! uroporphyrinogen-III synthase
relationship: has_gene_template MGI:98917 ! Uros (mouse)

[Term]
id: PR:P10746-1
name: uroporphyrinogen-III synthase isoform 1 (human)
def: "A uroporphyrinogen-III synthase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hUROS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10746-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038816 ! uroporphyrinogen-III synthase isoform 1

[Term]
id: PR:000038816
name: uroporphyrinogen-III synthase isoform 1
def: "A uroporphyrinogen-III synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10746-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "UROS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000017135 ! uroporphyrinogen-III synthase