[Term]
id: PR:000049730
name: E3 ubiquitin-protein ligase ZNRF3, signal peptide removed ubiquitinated form (human)
def: "An E3 ubiquitin-protein ligase ZNRF3 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9ULT6, 56-936, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641210]
comment: Category=organism-modification.
synonym: "hZNRF3/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000277806, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q9ULT6, 56-936, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4641210 "PR:000049730 located_in GO:0005886"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q9ULT6 ! E3 ubiquitin-protein ligase ZNRF3 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000018208
name: E3 ubiquitin-protein ligase ZNRF3
def: "A protein that is a translation product of the human ZNRF3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ZNRF3" EXACT PRO-short-label [PRO:DNx]
synonym: "RNF203" RELATED Gene-based []
synonym: "KIAA1133" RELATED Gene-based []
synonym: "RING finger protein 203" EXACT []
synonym: "zinc/RING finger protein 3" EXACT []
synonym: "RING-type E3 ubiquitin transferase ZNRF3" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q5SSZ7-1
name: E3 ubiquitin-protein ligase ZNRF3 isoform m1 (mouse)
def: "An E3 ubiquitin-protein ligase ZNRF3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5SSZ7-1." [PRO:DNx, UniProtKB:Q5SSZ7]
comment: Category=organism-sequence.
synonym: "mZNRF3/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5SSZ7-1
is_a: PR:Q5SSZ7 ! E3 ubiquitin-protein ligase ZNRF3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9ULT6-2
name: E3 ubiquitin-protein ligase ZNRF3 isoform h2 (human)
def: "An E3 ubiquitin-protein ligase ZNRF3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ULT6-2." [PRO:DNx, UniProtKB:Q9ULT6]
comment: Category=organism-sequence.
synonym: "hZNRF3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9ULT6-2
is_a: PR:Q9ULT6 ! E3 ubiquitin-protein ligase ZNRF3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9ULT6-1
name: E3 ubiquitin-protein ligase ZNRF3 isoform h1 (human)
def: "An E3 ubiquitin-protein ligase ZNRF3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ULT6-1." [PRO:DNx, UniProtKB:Q9ULT6]
comment: Category=organism-sequence.
synonym: "hZNRF3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9ULT6-1
is_a: PR:Q9ULT6 ! E3 ubiquitin-protein ligase ZNRF3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q5SSZ7-2
name: E3 ubiquitin-protein ligase ZNRF3 isoform m2 (mouse)
def: "An E3 ubiquitin-protein ligase ZNRF3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5SSZ7-2." [PRO:DNx, UniProtKB:Q5SSZ7]
comment: Category=organism-sequence.
synonym: "mZNRF3/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5SSZ7-2
is_a: PR:Q5SSZ7 ! E3 ubiquitin-protein ligase ZNRF3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9ULT6
name: E3 ubiquitin-protein ligase ZNRF3 (human)
def: "An E3 ubiquitin-protein ligase ZNRF3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9ULT6]
comment: Category=organism-gene.
synonym: "ZNRF3" RELATED Gene-based [UniProtKB:Q9ULT6]
synonym: "RNF203" RELATED Gene-based [UniProtKB:Q9ULT6]
synonym: "hZNRF3" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1133" RELATED Gene-based [UniProtKB:Q9ULT6]
synonym: "RING finger protein 203 (human)" EXACT [UniProtKB:Q9ULT6]
synonym: "zinc/RING finger protein 3 (human)" EXACT [UniProtKB:Q9ULT6]
synonym: "RING-type E3 ubiquitin transferase ZNRF3 (human)" EXACT [UniProtKB:Q9ULT6]
xref: Reactome:R-HSA-4641179 "PR:Q9ULT6 located_in GO:0005886"
xref: UniProtKB:Q9ULT6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000018208 ! E3 ubiquitin-protein ligase ZNRF3
relationship: has_gene_template HGNC:18126 ! ZNRF3 (human)

[Term]
id: PR:A5WWA0
name: E3 ubiquitin-protein ligase znrf3 (zebrafish)
def: "An E3 ubiquitin-protein ligase ZNRF3 that is encoded in the genome of zebrafish." [OMA:A5WWA0, PRO:DNx]
comment: Category=organism-gene.
synonym: "znrf3" RELATED Gene-based [UniProtKB:A5WWA0]
synonym: "z-ZNRF3" EXACT PRO-short-label [PRO:DNx]
synonym: "si:dkeyp-7c9.3" RELATED Gene-based [UniProtKB:A5WWA0]
synonym: "zinc/RING finger protein 3 (zebrafish)" EXACT [UniProtKB:A5WWA0]
synonym: "RING-type E3 ubiquitin transferase znrf3 (zebrafish)" EXACT [UniProtKB:A5WWA0]
xref: UniProtKB:A5WWA0
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000018208 ! E3 ubiquitin-protein ligase ZNRF3
relationship: has_gene_template ZFIN:ZDB-GENE-070705-263 ! znrf3 (zebrafish)

[Term]
id: PR:Q5SSZ7
name: E3 ubiquitin-protein ligase ZNRF3 (mouse)
def: "An E3 ubiquitin-protein ligase ZNRF3 that is encoded in the genome of mouse." [OMA:Q5SSZ7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Znrf3" RELATED Gene-based [UniProtKB:Q5SSZ7]
synonym: "mZNRF3" EXACT PRO-short-label [PRO:DNx]
synonym: "zinc/RING finger protein 3 (mouse)" EXACT [UniProtKB:Q5SSZ7]
synonym: "RING-type E3 ubiquitin transferase ZNRF3 (mouse)" EXACT [UniProtKB:Q5SSZ7]
xref: UniProtKB:Q5SSZ7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000018208 ! E3 ubiquitin-protein ligase ZNRF3
relationship: has_gene_template MGI:3039616 ! Znrf3 (mouse)