[Term]
id: PR:000025496
name: lipopolysaccharide receptor complex 2
def: "A lipopolysaccharide receptor complex that contains the soluble form of CD14, and the lipopolysaccharide (LPS) bound to it." [PMID:1281215, PMID:16176659, PMID:7681988]
comment: Category=complex. Note: The soluble form of CD14 is able to transfer the lipopolysaccharide to MD-2 in the tissues where the membrane form is absent.
synonym: "LPSR:2" EXACT PRO-short-label [PRO:DAN]
synonym: "TLR4MD2LPSCD14s complex" EXACT [TLR:AMM]
is_a: GO:0046696 ! lipopolysaccharide receptor complex
relationship: has_component CHEBI:16412 ! lipopolysaccharide
relationship: has_component PR:000002147 ! CD14 molecule isoform 1 cleaved 2 soluble form
relationship: has_component PR:000003299 ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1
relationship: has_component PR:000025492 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1