[Term]
id: PR:000025787
name: Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (human)
def: "A Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:O00206-1, 24-839, Asn-35/Asn-173/Asn-205/Asn-282/Asn-309/Asn-497/Asn-526/Asn-575/Asn-624, MOD:00160." [PMID:11706042, PMID:19252480]
comment: Category=organism-modification. Note: The Reactome cross-reference cites only glycosylations at positions 526 and 575, as these were found to be the key functional modifications. Nonetheless, structural studies indicate the modifications listed here provide a more-complete representation. [PRO:DAN, PMID:11706042]
synonym: "hTLR4/iso:1/SigPep-/NGlyco:1" EXACT PRO-short-label [PRO:DAN]
synonym: "Toll-like receptor 4 isoform 1 cleaved and glycosylated 1 (human)" EXACT []
synonym: "PRO_0000034722, Asn-35/Asn-173/Asn-205/Asn-282/Asn-309/Asn-497/Asn-526/Asn-575/Asn-624, MOD:00160" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:O00206-1, 24-839, Asn-35/Asn-173/Asn-205/Asn-282/Asn-309/Asn-497/Asn-526/Asn-575/Asn-624, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-166045 "PR:000025787 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025492 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine