[Term]
id: PR:000026741
name: cyclin D1:Cdk4 (human)
def: "A cyclin D1:Cdk4 whose components are encoded in the genome of human." [PRO:DAN, Reactome:R-HSA-113844]
comment: Category=organism-complex.
xref: Reactome:R-HSA-113844 "PR:000026741 located_in GO:0005654"
is_a: PR:000026740 ! cyclin D1:Cdk4
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000026623 {cardinality="1"} ! cell division protein kinase 4, initiator methionine removed form (human)
relationship: has_component PR:P24385 {cardinality="1"} ! G1/S-specific cyclin-D1 (human)

[Term]
id: PR:000026740
name: cyclin D1:Cdk4
def: "A cyclin-dependent protein kinase holoenzyme complex that has a cyclin-D1 regulatory subunit and a Cdk4 kinase subunit." [PRO:DAN]
comment: Category=complex.
is_a: GO:0000307 ! cyclin-dependent protein kinase holoenzyme complex
relationship: has_component PR:000005121 {cardinality="1"} ! G1/S-specific cyclin-D1
relationship: has_component PR:000019288 {cardinality="1"} ! cell division protein kinase 4, initiator methionine removed form