[Term]
id: PR:000026879
name: caspase-3 complex (human)
def: "A caspase-3 complex that is composed of two anti-parallel arranged heterodimers, each one formed by p12 and p17 subunits of caspase-3 in human." [PMID:9045680, Reactome:R-HSA-141647]
comment: Category=organism-complex.
synonym: "human active caspase-3" EXACT []
xref: Reactome:R-HSA-141647 "PR:000026879 located_in GO:0005829"
is_a: PR:000026878 ! caspase-3 complex
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000026876 {cardinality="2"} ! caspase-3 isoform 1 cleaved 1 (human)
relationship: has_component PR:000026877 {cardinality="2"} ! caspase-3 isoform 1 cleaved 2 (human)

[Term]
id: PR:000026878
name: caspase-3 complex
def: "A caspase complex that is composed of p12 and p17 subunits of caspase-3." [PMID:9045680, PMID:9202418]
comment: Category=complex.
synonym: "active caspase-3" EXACT []
is_a: GO:0008303 ! caspase complex
relationship: has_component PR:000002454 ! caspase-3 isoform 1 cleaved 1
relationship: has_component PR:000002455 ! caspase-3 isoform 1 cleaved 2