[Term]
id: PR:000027267
name: IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
def: "An IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 whose components are encoded in the genome of mouse." [PMID:12150927, TLR:AMM]
comment: Category=organism-complex. Requested by=TLR.
synonym: "IRAK3:IRAK1:IRAK4:MyD88:Mal:activated TLR4 (mouse)" EXACT []
is_a: PR:000027266 ! IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4
relationship: has_component CHEBI:16412 ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_component PR:000027171 ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:000027172 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:P22366-1 ! myeloid differentiation primary response protein MyD88 isoform 1 (mouse)
relationship: has_component PR:Q62406 ! interleukin-1 receptor-associated kinase 1 (mouse)
relationship: has_component PR:Q8K4B2 ! interleukin-1 receptor-associated kinase 3 (mouse)
relationship: has_component PR:Q8R4K2 ! interleukin-1 receptor-associated kinase 4 (mouse)
relationship: has_component PR:Q99JY1 ! Toll/interleukin-1 receptor domain-containing adapter protein (mouse)

[Term]
id: PR:000027266
name: IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4
def: "A protein-containing complex that is composed of the activated TLR4 receptor, Mal, MyD88, IRAK1, IRAK4 and the negative regulator IRAK3 (or IRAK-M)." [PMID:12150927, TLR:AMM]
comment: Category=complex. Requested by=TLR.
synonym: "IRAK3:IRAK1:IRAK4:MyD88:Mal:activated TLR4" EXACT []
synonym: "IRAK-M:IRAK1:IRAK4:MyD88:Mal:activated TLR4" EXACT []
is_a: GO:0032991 ! protein-containing complex