[Term]
id: PR:000028699
name: IRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, Ticam1, a phosphorylated kinase tbk1 or IKK epsilon and the non-phosphorylated form of IRF3 or IRF7. IRF3 and IRF7 are recruited via phosphorylated tbk1 and IKK epsilon." [Reactome:REACT_27000]
comment: Category=complex. Requested by=TLR.
synonym: "activated TLR4:TRAM:TRIF:p-TBK1/p-IKKE:IRF3/IRF7" RELATED [Reactome:REACT_27000]
is_a: GO:0032991 ! protein-containing complex