[Term]
id: PR:000035511
name: BUB1B:BUB3:MAD2:CDC20 complex (human)
def: "A mitotic checkpoint complex whose components are encoded in the genome of human." [PMID:20624902, PRO:KER, Reactome:R-HSA-141440]
comment: Category=organism-complex. Note: This complex uses the activated form of MAD2. [PRO:DAN, PMID:25303117]
synonym: "hMCC" BROAD [PRO:DNx]
synonym: "human mitotic checkpoint complex" EXACT []
synonym: "hBUBR1:hBUB3:MAD2*:CDC20 complex (human)" EXACT [Reactome:R-HSA-141440]
xref: Reactome:R-HSA-141440 "PR:000035511 located_in GO:0005829"
is_a: GO:0033597 ! mitotic checkpoint complex
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000042259 ! mitotic spindle assembly checkpoint protein MAD2A, initiator methionine removed form (human)
relationship: has_component PR:O43684 ! mitotic checkpoint protein BUB3 (human)
relationship: has_component PR:O60566 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human)
relationship: has_component PR:Q12834 ! cell division cycle protein 20 homolog (human)