[Term] id: PR:000036068 name: caspase-8 complex (human) def: "A caspase-8 complex that is composed of two anti-parallel arranged heterodimers, each one formed by p10 and p18 subunits of caspase-8 in human." [PMID:9184224] comment: Category=organism-complex. synonym: "human active caspase-8" EXACT [] is_a: PR:000036067 ! caspase-8 complex relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: has_component PR:000036063 {cardinality="2"} ! caspase-8 isoform 1 cleaved 1 (human) relationship: has_component PR:000036065 {cardinality="2"} ! caspase-8 isoform 1 cleaved 2 (human) [Term] id: PR:000036067 name: caspase-8 complex def: "A caspase complex that is composed of two heterodimers of p10 and p18 subunits of caspase-8." [PMID:9184224] comment: Category=complex. synonym: "active caspase-8" EXACT [] is_a: GO:0008303 ! caspase complex