[Term]
id: PR:000036098
name: ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1, TRAF3, TANK linked to Lys-63 polyubiquitin and IKKE." [TLR:AMM]
comment: Category=complex. Requested by=TLR.
synonym: "K63-poly-Ub-tank:TRAF3:TRIF:TRAM:activated TLR4" BROAD [PRO:DNx]
is_a: GO:0032991 ! protein-containing complex

[Term]
id: PR:000036099
name: ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
def: "An ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of mouse." [TLR:AMM]
comment: Category=organism-complex. Requested by=TLR.
synonym: "ikke:K63-poly-Ub-tank:TRAF3:TRIF:TRAM:activated TLR4 (mouse)" EXACT []
is_a: PR:000036098 ! ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex
relationship: has_component CHEBI:16412 ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_component PR:000027171 ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:000027172 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:000036091 ! TRAF family member-associated NF-kappa-B activator isoform 1 K63-polyubiquitinated form (mouse)
relationship: has_component PR:Q60803 ! TNF receptor-associated factor 3 (mouse)
relationship: has_component PR:Q80UF7 ! TIR domain-containing adapter molecule 1 (mouse)
relationship: has_component PR:Q8BJQ4 ! TIR domain-containing adapter molecule 2 (mouse)
relationship: has_component PR:Q9R0T8 ! inhibitor of nuclear factor kappa-B kinase subunit epsilon (mouse)