[Term] id: PR:000036098 name: ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex def: "A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1, TRAF3, TANK linked to Lys-63 polyubiquitin and IKKE." [TLR:AMM] comment: Category=complex. Requested by=TLR. synonym: "K63-poly-Ub-tank:TRAF3:TRIF:TRAM:activated TLR4" BROAD [PRO:DNx] is_a: GO:0032991 ! protein-containing complex [Term] id: PR:000036099 name: ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse) def: "An ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of mouse." [TLR:AMM] comment: Category=organism-complex. Requested by=TLR. synonym: "ikke:K63-poly-Ub-tank:TRAF3:TRIF:TRAM:activated TLR4 (mouse)" EXACT [] is_a: PR:000036098 ! ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex relationship: has_component CHEBI:16412 ! lipopolysaccharide relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus relationship: has_component PR:000027171 ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse) relationship: has_component PR:000027172 ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse) relationship: has_component PR:000036091 ! TRAF family member-associated NF-kappa-B activator isoform 1 K63-polyubiquitinated form (mouse) relationship: has_component PR:Q60803 ! TNF receptor-associated factor 3 (mouse) relationship: has_component PR:Q80UF7 ! TIR domain-containing adapter molecule 1 (mouse) relationship: has_component PR:Q8BJQ4 ! TIR domain-containing adapter molecule 2 (mouse) relationship: has_component PR:Q9R0T8 ! inhibitor of nuclear factor kappa-B kinase subunit epsilon (mouse)