[Term]
id: PR:000037312
name: tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 3, TICAM1 (TRIF), TRAF3, TANK, TBK1, and IKKE." [PMID:12133833, PMID:17327220, TLR:AMM]
comment: Category=complex. Requested by=TLR.
synonym: "TLR3TLR3dsRNATriftraf3TBK1tankIKKe" EXACT []
is_a: GO:0032991 ! protein-containing complex

[Term]
id: PR:000037313
name: tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)
def: "A tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex whose components are encoded in the genome of mouse." [PMID:16306936, PMID:16306937, TLR:AMM]
comment: Category=organism-complex. Requested by=TLR.
synonym: "TLR3TLR3dsRNATriftraf3TBK1tankIKKe (mouse)" EXACT []
is_a: PR:000037312 ! tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex
relationship: has_component CHEBI:67208 {cardinality="1"} ! dsRNA
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_component PR:000037789 {cardinality="2"} ! Toll-like receptor 3, signal peptide removed form (mouse)
relationship: has_component PR:P70347 ! TRAF family member-associated NF-kappa-B activator (mouse)
relationship: has_component PR:Q60803 {cardinality="2"} ! TNF receptor-associated factor 3 (mouse)
relationship: has_component PR:Q80UF7 {cardinality="2"} ! TIR domain-containing adapter molecule 1 (mouse)
relationship: has_component PR:Q9R0T8 ! inhibitor of nuclear factor kappa-B kinase subunit epsilon (mouse)
relationship: has_component PR:Q9WUN2 ! serine/threonine-protein kinase TBK1 (mouse)