[Term]
id: PR:000037353
name: IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 3 (TLR3), Ticam1 (TRIF), TRAF3 linked to Lys-63 polyubiquitin, phosphorylated TBK1 and IRF3 unphosphorylated." [PMID:14517278, PMID:14739303, PMID:16281057, Reactome:REACT_27000]
comment: Category=complex. Requested by=TLR.
synonym: "activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF3" RELATED [Reactome:REACT_27000]
is_a: GO:0032991 ! protein-containing complex