[Term]
id: PR:000037366
name: fadd:rip1:ticam1:activated TLR3 complex (human)
def: "An fadd:rip1:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PMID:15814722, PMID:21737330, PRO:VS, Reactome:R-HSA-2562577]
comment: Category=organism-complex. Requested by=TLR.
synonym: "activated TLR3:TRIF:RIP1:FADD (human)" EXACT [Reactome:R-HSA-2562577]
is_a: PR:000037365 ! fadd:rip1:ticam1:activated TLR3 complex
relationship: has_component CHEBI:67208 {cardinality="1"} ! dsRNA
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000037305 {cardinality="2"} ! Toll-like receptor 3, signal peptide removed form (human)
relationship: has_component PR:Q13158 {cardinality="2"} ! FAS-associated death domain protein (human)
relationship: has_component PR:Q13546 {cardinality="2"} ! receptor-interacting serine/threonine-protein kinase 1 (human)
relationship: has_component PR:Q8IUC6 {cardinality="2"} ! TIR domain-containing adapter molecule 1 (human)

[Term]
id: PR:000037365
name: fadd:rip1:ticam1:activated TLR3 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 3 (TLR3), ticam1 (TRIF), ripk1 (RIP1), and fadd." [Reactome:R-HSA-2562577]
comment: Category=complex. Requested by=TLR.
synonym: "activated TLR3:TRIF:RIP1:FADD" EXACT [Reactome:R-HSA-2562577]
is_a: GO:0032991 ! protein-containing complex