[Term]
id: PR:000045222
name: histone H3.1, initiator methionine removed dimethylated 8 (human)
def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-37, MOD:00084." [HIstome_var_Hs:Histone_H3.1, PMID:16861263, PMID:21187428, PMID:21239496, PMID:21310926, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H3.1:H3K36me2" BROAD [HIstome_ptm_Hs:H3K36me2]
synonym: "hH3.1/InitMet-/Me2:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P68431, 2-136, Lys-37, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4722125 "PR:000045222 located_in GO:0005654"
is_a: PR:P68431 ! histone H3.1 (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine