[Term]
id: PR:000045263
name: histone H3.2, initiator methionine removed dimethylated 6 (human)
def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00084." [HIstome_var_Hs:Histone_H3.2, PMID:12232854, PMID:15153943, PMID:16861263, PMID:17314394, PMID:17901401, PMID:18552846, PMID:18776137, PMID:18850007, PMID:19349354, PMID:19349354, PMID:19739128, PRO:DAN, PRO:JPB, PRO:JR]
comment: Category=organism-modification.
synonym: "H3.2:H3K9me2" BROAD [HIstome_ptm_Hs:H3K9me2]
synonym: "hH3.2/InitMet-/Me2:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-427407 "PR:000045263 located_in GO:0005654"
xref: Reactome:R-HSA-4724280 "PR:000045263 located_in GO:0005654"
xref: TDR:12360
is_a: PR:Q71DI3 ! histone H3.2 (human)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine