[Term]
id: PR:000049844
name: TTK activation loop-phosphorylated form (human)
def: "A dual specificity protein kinase TTK (human) that has been phosphorylated on one of three sites within the activation loop, at positions equivalent to Thr-675 or Thr-676 or Ser-677 of the amino acid sequence represented by UniProtKB:P33981-1. Example: UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047)|Ser-677, MOD:00046." [PMID:17728254, PMID:18923149, PMID:1912069, PRO:KER]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17728254). Evidence=(ECO:0000006, based on PMID:1912069). Evidence=(ECO:0000006, based on PMID:18923149). Kinase=("TTK"; PR:P33981; Thr-675). Kinase=("TTK"; PR:P33981; Thr-676). Kinase=("TTK"; PR:P33981; Ser-677).
synonym: "hTTK/pActloop" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047)|Ser-677, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P33981 ! dual specificity protein kinase TTK (human)
relationship: has_part MOD:00696 ! phosphorylated residue
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens