[Term]
id: PR:000050160
name: IgA2 immunoglobulin complex, circulating (human)
def: "An IgA immunoglobulin complex, circulating composed of two identical immunoglobulin heavy chains of the secretory isoform of the IgA2 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL. Note: Human circulating IgA2 is only found as a monomeric form.
synonym: "hIgA2/circulating" EXACT PRO-short-label [PRO:DAN]
synonym: "IgA antibody (human)" BROAD [PRO:ADD, GOC:add]
synonym: "IgA2 antibody (human)" EXACT [PRO:ADD, GOC:add]
synonym: "monomeric IgA antibody (human)" BROAD [PRO:ADD, GOC:add]
synonym: "monomeric IgA2 antibody (human)" EXACT [PRO:ADD, GOC:add]
synonym: "monomeric IgA2 immunoglobulin complex (human)" EXACT [PRO:ADD, GOC:add]
is_a: GO:0071746 ! IgA immunoglobulin complex, circulating
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: has_component PR:000050378 {cardinality="2"} ! IgA2 heavy chain protein, secretory isoform (human)