[Term]
id: PR:000050162
name: IgA2 B cell receptor complex (human)
def: "An IgA2 immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the membrane-bound isoform of the IgA2 isotype, two identical immunoglobulin light chains (kappa or lambda), and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL.
synonym: "surface IgA (human)" BROAD [PRO:ADD, GOC:add]
synonym: "surface IgA2 (human)" EXACT [PRO:ADD, GOC:add]
synonym: "hIgA2/B-cell-receptor" EXACT PRO-short-label [PRO:DAN]
synonym: "membrane-bound IgA (human)" BROAD [PRO:ADD, GOC:add]
synonym: "membrane-bound IgA2 (human)" EXACT [PRO:ADD, GOC:add]
is_a: GO:0071747 ! IgA B cell receptor complex
relationship: part_of CL:0000236 ! B cell
relationship: part_of GO:0005886 ! plasma membrane
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: has_component PR:000050379 {cardinality="2"} ! IgA2 heavy chain protein, membrane bound isoform (human)
relationship: has_component PR:P11912 {cardinality="1"} ! B-cell antigen receptor complex-associated protein alpha chain (human)
relationship: has_component PR:P40259 {cardinality="1"} ! B-cell antigen receptor complex-associated protein beta chain (human)