[Term]
id: PR:000050311
name: IgG3 immunoglobulin complex, circulating (human)
def: "An IgG3 immunoglobulin complex (human) that is composed of two identical immunoglobulin heavy chains of an IgG3 isotype of the secretory isoform and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, PMID:25368619, PRO:ADD]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL.
synonym: "hIgG3/circulating" EXACT PRO-short-label [PRO:ADD, GOC:add]
synonym: "IgG antibody (human)" BROAD [PRO:ADD, GOC:add]
synonym: "IgG3 antibody (human)" EXACT [PRO:ADD, GOC:add]
is_a: PR:000050307 ! IgG3 immunoglobulin complex (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: has_component PR:000050299 {cardinality="2"} ! IgG3 heavy chain protein, secretory isoform (human)