[Term]
id: PR:000060193
name: histone H3.3 type a trimethylated 2 (Dictyostelium discoideum)
def: "A histone H3.3 type a (Dictyostelium discoideum) that has been trimethylated at the position equivalent to Lys-40 of the amino acid sequence represented by UniProtKB:O15819. Note that the indicated residue is called Lys-36 in the literature, based on sequence numbering that accounts for a removed initiator methionine and that the protein in Dictyostelium discoideum contains a three amino-acid insertion relative to most orthologs. UniProtKB:O15819, Lys-40, MOD:00083." [PMID:22600736, PRO:DAN, dictyBase:PF]
comment: Category=organism-modification. Requested by=dictyBase. Enzyme=("set2"; PR:Q55FF7, Lys-40). Evidence=(ECO:0000006, based on PMID:22600736). Note: In vivo. Contains H3aK36me3 (or, broadly, H3K36me3).
synonym: "Dicty-H3a/Me3:2" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:O15819, Lys-40, MOD:00083" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:O15819 ! histone H3.3 type a (Dictyostelium discoideum)
relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine
relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum