[Term]
id: PR:000060210
name: histone H2AX acetylated and dimethylated 1 (Dictyostelium discoideum)
def: "A histone H2AX (Dictyostelium discoideum) that has been acetylated at the position equivalent to Ser-2 and dimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q54WG6. Note that the indicated residues are called Ser-1 and Lys-9, respectively, in the literature, based on sequence numbering that accounts for a removed initiator methionine. UniProtKB:Q54WG6, Ser-2, MOD:00647|Lys-10, MOD:00084." [PMID:33947439, PRO:DAN, dictyBase:PF]
comment: Category=organism-modification. Requested by=dictyBase. Note: In vivo. Contains H2AXS1ac and H2AXK9me2.
synonym: "Dicty-H2AX/AcMe2:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q54WG6, Ser-2, MOD:00647|Lys-10, MOD:00084" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:Q54WG6 ! histone H2AX (Dictyostelium discoideum)
relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine
relationship: has_part MOD:00647 ! monoacetylated L-serine
relationship: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum