PRO_ID	Object_term	Object_syny	Modifier	Relation	Ontology_ID	Ontology_term	Relative_to	Interaction_with	Evidence_source	Evidence_code	Taxon	Inferred_from	DB_ID	Date	Assigned_by	Comment
PR:000000621	TGF-beta 1 sequence variant R218C cleaved 1 (human)	hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950		enables	GO:0042803	protein homodimerization activity			PMID:11062463|PMID:12493741|PMID:12843182	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_017608	20080301	PRO:CNA	
PR:000000621	TGF-beta 1 sequence variant R218C cleaved 1 (human)	hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950		enables	GO:0005160	transforming growth factor beta receptor binding			PMID:11278244	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_017608	20080301	PRO:CNA	
PR:000000621	TGF-beta 1 sequence variant R218C cleaved 1 (human)	hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950	increased	enables	GO:0008083	growth factor activity	PR:000000616		PMID:11062463|PMID:12493741|PMID:12843182	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_017608	20080301	PRO:CNA	
PR:000000621	TGF-beta 1 sequence variant R218C cleaved 1 (human)	hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950		acts_upstream_of_or_within	GO:0007179	transforming growth factor beta receptor signaling pathway			PMID:11062463|PMID:12493741|PMID:12843182	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_017608	20080301	PRO:CNA	
PR:000000621	TGF-beta 1 sequence variant R218C cleaved 1 (human)	hTGFB1/var:R218C/Clv:1|TGF-beta 1 sequence variant 3 cleaved 1 (human)|UniProtKB:P01137, 279-390, Arg-218, CHEBI:29950		located_in	GO:0005615	extracellular space			PMID:11062463|PMID:12493741|PMID:12843182	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_017608	20080301	PRO:CNA