PRO_ID Object_term Object_syny Modifier Relation Ontology_ID Ontology_term Relative_to Interaction_with Evidence_source Evidence_code Taxon Inferred_from DB_ID Date Assigned_by Comment PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac acts_upstream_of_or_within GO:0030103 vasopressin secretion PMID:12777254 IMP NCBITaxon:10090 MGI:2667379 UniProtKB:Q9EPK8 20080923 MGI:HJD PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac enables GO:0005034 osmosensor activity PMID:11025659 IMP NCBITaxon:10090 MGI:2667379 UniProtKB:Q9EPK8 20080923 MGI:HJD PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac acts_upstream_of_or_within GO:0047484 regulation of response to osmotic stress PMID:12777254 IMP NCBITaxon:10090 MGI:2667379 UniProtKB:Q9EPK8 20080923 MGI:HJD PR:Q9EPK8 transient receptor potential cation channel subfamily V member 4 (mouse) mTRPV4|Osm-9-like TRP channel 4 (mouse)|OTRPC4 (mouse)|transient receptor potential protein 12 (mouse)|Trp12|TRP12 (mouse)|Trpv4|TrpV4 (mouse)|vanilloid receptor-like channel 2 (mouse)|vanilloid receptor-like protein 2 (mouse)|vanilloid receptor-related osmotically-activated channel (mouse)|VR-OAC (mouse)|Vrl2|Vroac acts_upstream_of_or_within GO:0042538 hyperosmotic salinity response PMID:12777254 IMP NCBITaxon:10090 MGI:2667379 UniProtKB:Q9EPK8 20080923 MGI:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) located_in GO:0005886 plasma membrane PMID:14517216 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 MGI:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) contributes_to enables GO:0005262 calcium channel activity PMID:11025659 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 MGI:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) acts_upstream_of_or_within GO:0007231 osmosensory signaling pathway PMID:11025659 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 MGI:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) acts_upstream_of_or_within GO:0006970 response to osmotic stress PMID:11025659 IDA NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 MGI:HJD PR:Q9EPK8-1 transient receptor potential cation channel subfamily V member 4 isoform A (mouse) mTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (mouse)|Trpv4 isoform 1 (mouse) enables GO:0005515 protein binding PR:O88735 PMID:14517216 IPI NCBITaxon:10090 UniProtKB:Q9EPK8-1 20080923 MGI:HJD PR:Q9HBA0-1 transient receptor potential cation channel subfamily V member 4 isoform A (human) hTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (human)|TRPV4 isoform 1 (human) located_in GO:0005886 plasma membrane PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-1 20081015 PRO:CNA PR:Q9HBA0-1 transient receptor potential cation channel subfamily V member 4 isoform A (human) hTRPV4/iso:A|transient receptor potential cation channel subfamily V member 4 isoform 1 (human)|TRPV4 isoform 1 (human) enables GO:0042802 identical protein binding PR:Q9HBA0-1 PMID:16293632 IPI NCBITaxon:9606 UniProtKB:Q9HBA0-1 20081015 PRO:CNA PR:Q9HBA0-2 transient receptor potential cation channel subfamily V member 4 isoform B (human) hTRPV4/iso:2|hTRPV4/iso:B|transient receptor potential cation channel subfamily V member 4 isoform 2 (human)|transient receptor potential cation channel subfamily V member 4 isoform OTRPC4beta (human) located_in GO:0005783 endoplasmic reticulum PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-2 20081015 PRO:CNA PR:Q9HBA0-4 transient receptor potential cation channel subfamily V member 4 isoform C (human) hTRPV4/iso:4|hTRPV4/iso:C|transient receptor potential cation channel subfamily V member 4 isoform 4 (human) located_in GO:0005783 endoplasmic reticulum PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-4 20081015 PRO:CNA PR:Q9HBA0-5 transient receptor potential cation channel subfamily V member 4 isoform D (human) hTRPV4/iso:5|hTRPV4/iso:D|transient receptor potential cation channel subfamily V member 4 isoform 5 (human) located_in GO:0005886 plasma membrane PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-5 20081015 PRO:CNA PR:Q9HBA0-5 transient receptor potential cation channel subfamily V member 4 isoform D (human) hTRPV4/iso:5|hTRPV4/iso:D|transient receptor potential cation channel subfamily V member 4 isoform 5 (human) enables GO:0042802 identical protein binding PR:Q9HBA0-5 PMID:16293632 IPI NCBITaxon:9606 UniProtKB:Q9HBA0-5 20081015 PRO:CNA PR:Q9HBA0-6 transient receptor potential cation channel subfamily V member 4 isoform E (human) hTRPV4/iso:6|hTRPV4/iso:E|transient receptor potential cation channel subfamily V member 4 isoform 6 (human) located_in GO:0005783 endoplasmic reticulum PMID:16293632 IDA NCBITaxon:9606 UniProtKB:Q9HBA0-6 20081015 PRO:CNA