PRO_ID Object_term Object_syny Modifier Relation Ontology_ID Ontology_term Relative_to Interaction_with Evidence_source Evidence_code Taxon Inferred_from DB_ID Date Assigned_by Comment PR:000037463 LPS:secreted CD14 alpha (human) h-LPS:sCD14alpha|sCD14/LPS complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037463 LPS:secreted CD14 alpha (human) h-LPS:sCD14alpha|sCD14/LPS complex (human) located_in GO:0005615 extracellular space Reactome:REACT_7856 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037464 LPS:GPI-anchored CD14 complex (human) h-LPS:mCD14|mCD14/LPS complex (human) located_in GO:0005886 plasma membrane Reactome:REACT_7856 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037464 LPS:GPI-anchored CD14 complex (human) h-LPS:mCD14|mCD14/LPS complex (human) acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894 EXP NCBITaxon:9606 20140513 PRO:VS PR:000037466 LPS:transmembrane CD14 complex (chicken) acts_upstream_of_or_within GO:0045429 positive regulation of nitric oxide biosynthetic process PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA Evidence=ECO:0000305, PMID:24034933 shows the increase of CD14 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex LPS:CD14 has been inferred by curator based on expression data and conserved TLR signaling response. Note=In response to laryngotracheitis virus. PR:000037466 LPS:transmembrane CD14 complex (chicken) acts_upstream_of_or_within GO:0051607 defense response to virus PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA Evidence=ECO:0000305, PMID:24034933 shows the increase of CD14 in cell surface in response to LPS in viral infection. It also shows the production of NO as a downstream effect. Evidence=ECO:0000305, the complex LPS:CD14 has been inferred by curator based on expression data and conserved TLR signaling response. Note=In response to laryngotracheitis virus. PR:000037466 LPS:transmembrane CD14 complex (chicken) located_in GO:0009986 cell surface PMID:18761368|PMID:24034933 EXP NCBITaxon:9031 20140718 PRO:CNA